Low-intensity pulsed ultrasound inhibits fibroblast-like synoviocyte proliferation and reduces synovial fibrosis by regulating Wnt/β-catenin signaling

Low-intensity pulsed ultrasound inhibits fibroblast-like synoviocyte proliferation and reduces synovial fibrosis by regulating Wnt/β-catenin signaling

Objective: Synovial fibrosis is a characteristic symptom of osteoarthritis (OA), which is closely associated with joint pain and stiffness. Previous studies have reported that low-intensity pulsed ultrasound (LIPUS) can alleviate cartilage degradation in OA. However, the functions and mechanisms of...

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Bibliographic Details
Main Authors: Bo Liao, Mengtong Guan, Qiaoyan Tan, Gailan Wang, Ruobin Zhang, Junlan Huang, Mi Liu, Hong Chen, Kaiting Li, Dingqun Bai, Ying Zhu
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of Orthopaedic Translation
Subjects:
Cell proliferation
Fibroblast-like synoviocyte
Low-intensity pulsed ultrasound
Osteoarthritis
Synovial fibrosis
Wnt/β-catenin signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X21000644

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http://www.sciencedirect.com/science/article/pii/S2214031X21000644

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