Construction of an Isonucleoside on a 2,6-Dioxobicyclo[3.2.0]-heptane Skeleton
We have built a new isonucleoside derivative on a 2,6-dioxobicyclo[3.2.0]heptane skeleton as a potential anti-HIV agent. To synthesize the target compound, an acetal-protected dihydroxyacetone was first converted to a 2,3-epoxy-tetrahydrofuran derivative. Introduction of an azide group, followed by...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-03-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/20/3/4623 |