Axial Myopia Is Associated with Visual Field Prognosis of Primary Open-Angle Glaucoma.
To identify whether myopia was associated with the visual field (VF) progression of primary open-angle glaucoma (POAG).A total of 270 eyes of 270 POAG followed up for more than 3 years with ≥9 reliable VFs by Octopus perimetry were retrospectively reviewed. Myopia was divided into: mild myopia (-2.9...
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doaj-8b69b9dcdd734874852f4115b0cab4642020-11-24T21:50:35ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01107e013318910.1371/journal.pone.0133189Axial Myopia Is Associated with Visual Field Prognosis of Primary Open-Angle Glaucoma.Chen QiuShaohong QianXinghuai SunChuandi ZhouFanrong MengTo identify whether myopia was associated with the visual field (VF) progression of primary open-angle glaucoma (POAG).A total of 270 eyes of 270 POAG followed up for more than 3 years with ≥9 reliable VFs by Octopus perimetry were retrospectively reviewed. Myopia was divided into: mild myopia (-2.99 diopter [D], 0), moderate myopia (-5.99, 3.00 D), marked myopia (-9.00, -6.00 D) and non-myopia (0 D or more). An annual change in the mean defect (MD) slope >0.22 dB/y and 0.30 dB/y was defined as fast progression, respectively. Logistic regression was performed to determine prognostic factors for VF progression.For the cutoff threshold at 0.22 dB/y, logistic regression showed that vertical cup-to-disk ratio (VCDR; p = 0.004) and the extent of myopia (p = 0.002) were statistically significant. When logistic regression was repeated after excluding the extent of myopia, axial length (AL; p = 0.008, odds ratio [OR] = 0.796) reached significance, as did VCDR (p = 0.001). Compared to eyes with AL≤23 mm, the OR values were 0.334 (p = 0.059), 0.309 (p = 0.044), 0.266 (p = 0.019), 0.260 (p = 0.018), respectively, for 23 <AL≤24 mm, 24 <AL≤25 mm, 25 <AL ≤26 mm, and AL>26 mm. The significance of vertical cup-to-disk ratio of (p = 0.004) and the extent of myopia (p = 0.008) did not change for the cutoff threshold at 0.30dB/y.VCDR and myopia were associated with VF prognosis of POAG. Axial myopia may be a protective factor against VF progression.http://europepmc.org/articles/PMC4516304?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chen Qiu Shaohong Qian Xinghuai Sun Chuandi Zhou Fanrong Meng |
spellingShingle |
Chen Qiu Shaohong Qian Xinghuai Sun Chuandi Zhou Fanrong Meng Axial Myopia Is Associated with Visual Field Prognosis of Primary Open-Angle Glaucoma. PLoS ONE |
author_facet |
Chen Qiu Shaohong Qian Xinghuai Sun Chuandi Zhou Fanrong Meng |
author_sort |
Chen Qiu |
title |
Axial Myopia Is Associated with Visual Field Prognosis of Primary Open-Angle Glaucoma. |
title_short |
Axial Myopia Is Associated with Visual Field Prognosis of Primary Open-Angle Glaucoma. |
title_full |
Axial Myopia Is Associated with Visual Field Prognosis of Primary Open-Angle Glaucoma. |
title_fullStr |
Axial Myopia Is Associated with Visual Field Prognosis of Primary Open-Angle Glaucoma. |
title_full_unstemmed |
Axial Myopia Is Associated with Visual Field Prognosis of Primary Open-Angle Glaucoma. |
title_sort |
axial myopia is associated with visual field prognosis of primary open-angle glaucoma. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2015-01-01 |
description |
To identify whether myopia was associated with the visual field (VF) progression of primary open-angle glaucoma (POAG).A total of 270 eyes of 270 POAG followed up for more than 3 years with ≥9 reliable VFs by Octopus perimetry were retrospectively reviewed. Myopia was divided into: mild myopia (-2.99 diopter [D], 0), moderate myopia (-5.99, 3.00 D), marked myopia (-9.00, -6.00 D) and non-myopia (0 D or more). An annual change in the mean defect (MD) slope >0.22 dB/y and 0.30 dB/y was defined as fast progression, respectively. Logistic regression was performed to determine prognostic factors for VF progression.For the cutoff threshold at 0.22 dB/y, logistic regression showed that vertical cup-to-disk ratio (VCDR; p = 0.004) and the extent of myopia (p = 0.002) were statistically significant. When logistic regression was repeated after excluding the extent of myopia, axial length (AL; p = 0.008, odds ratio [OR] = 0.796) reached significance, as did VCDR (p = 0.001). Compared to eyes with AL≤23 mm, the OR values were 0.334 (p = 0.059), 0.309 (p = 0.044), 0.266 (p = 0.019), 0.260 (p = 0.018), respectively, for 23 <AL≤24 mm, 24 <AL≤25 mm, 25 <AL ≤26 mm, and AL>26 mm. The significance of vertical cup-to-disk ratio of (p = 0.004) and the extent of myopia (p = 0.008) did not change for the cutoff threshold at 0.30dB/y.VCDR and myopia were associated with VF prognosis of POAG. Axial myopia may be a protective factor against VF progression. |
url |
http://europepmc.org/articles/PMC4516304?pdf=render |
work_keys_str_mv |
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1725882905988694016 |