The evolution of spinal/epidural neostigmine in clinical application: Thoughts after two decades
Since the first clinical application of analgesia following spinal anticholinesterase by 1940′s, several clinical double-blind studies have been conducted to date, where intrathecal doses of neostigmine in humans ranged from 750 to 1 μg, due to side-effects. Conversely, epidural neostigmine has been...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Saudi Journal of Anaesthesia |
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| Online Access: | http://www.saudija.org/article.asp?issn=1658-354X;year=2015;volume=9;issue=1;spage=71;epage=81;aulast=Lauretti |