Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews
Introduction: This article is an attempt to provide an overview of systematic reviews to determine the efficacy of CQ10 supplementation in the treatment of patients with cardiovascular diseases (CVD). Method and material: All reviews were identified through a systematic search of the following datab...
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doaj-8b793b0cf9d04122a026ffbd6d581b0d2020-11-25T00:13:47ZengElsevierIndian Heart Journal0019-48322018-07-0170S111S117Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviewsMehdi Jafari0Seyed Masood Mousavi1Asra Asgharzadeh2Neda Yazdani3Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran; Health Services Management Department, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, IranSchool of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran; Corresponding author.School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran; Health Technology Assessment Group (HTAG), Universal Scientific Education and Research Network (USERN), Tehran, IranTehran University of Medical Sciences, Tehran, IranIntroduction: This article is an attempt to provide an overview of systematic reviews to determine the efficacy of CQ10 supplementation in the treatment of patients with cardiovascular diseases (CVD). Method and material: All reviews were identified through a systematic search of the following databases: Cochrane, DARE, Ovid, EMBASE, ISI Web of Knowledge, and PubMed. Check references studies and the quality of the studies was assessed by means of AMSTTAR. No meta-analyses were performed due to the heterogeneity of studies. Result: Extracted data for Seven systematic reviews for primary outcomes, net changes in cardiac output, cardiac index, New York Heart Association functional classification, improved survival, based on existing evidence, there is a case for use of CoQ10 as an adjunctive therapy in congestive heart failure, especially in those patients unable to tolerate mainstream medical therapies. Conclusion: Evidence suggests that the CoQ10 supplement may be a useful tool for managing patients with heart failure. Keywords: Cardiovascular, Systematic review, Coenzyme Q10http://www.sciencedirect.com/science/article/pii/S0019483217308696 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mehdi Jafari Seyed Masood Mousavi Asra Asgharzadeh Neda Yazdani |
spellingShingle |
Mehdi Jafari Seyed Masood Mousavi Asra Asgharzadeh Neda Yazdani Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews Indian Heart Journal |
author_facet |
Mehdi Jafari Seyed Masood Mousavi Asra Asgharzadeh Neda Yazdani |
author_sort |
Mehdi Jafari |
title |
Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews |
title_short |
Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews |
title_full |
Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews |
title_fullStr |
Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews |
title_full_unstemmed |
Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews |
title_sort |
coenzyme q10 in the treatment of heart failure: a systematic review of systematic reviews |
publisher |
Elsevier |
series |
Indian Heart Journal |
issn |
0019-4832 |
publishDate |
2018-07-01 |
description |
Introduction: This article is an attempt to provide an overview of systematic reviews to determine the efficacy of CQ10 supplementation in the treatment of patients with cardiovascular diseases (CVD). Method and material: All reviews were identified through a systematic search of the following databases: Cochrane, DARE, Ovid, EMBASE, ISI Web of Knowledge, and PubMed. Check references studies and the quality of the studies was assessed by means of AMSTTAR. No meta-analyses were performed due to the heterogeneity of studies. Result: Extracted data for Seven systematic reviews for primary outcomes, net changes in cardiac output, cardiac index, New York Heart Association functional classification, improved survival, based on existing evidence, there is a case for use of CoQ10 as an adjunctive therapy in congestive heart failure, especially in those patients unable to tolerate mainstream medical therapies. Conclusion: Evidence suggests that the CoQ10 supplement may be a useful tool for managing patients with heart failure. Keywords: Cardiovascular, Systematic review, Coenzyme Q10 |
url |
http://www.sciencedirect.com/science/article/pii/S0019483217308696 |
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