The Causal Role of Mitochondrial Dynamics in Regulating Insulin Resistance in Diabetes: Link through Mitochondrial Reactive Oxygen Species

The Causal Role of Mitochondrial Dynamics in Regulating Insulin Resistance in Diabetes: Link through Mitochondrial Reactive Oxygen Species

Background. Mitochondrial dynamics (mtDYN) has been proposed as a bridge between mitochondrial dysfunction and insulin resistance (IR), which is involved in the pathogenesis of type 2 diabetes (T2D). Our previous study has identified that mitochondrial DNA (mtDNA) haplogroup B4 is a T2D-susceptible...

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Bibliographic Details
Main Authors:	Hung-Yu Lin, Shao-Wen Weng, Yen-Hsiang Chang, Yu-Jih Su, Chih-Min Chang, Chia-Jen Tsai, Feng-Chih Shen, Jiin-Haur Chuang, Tsu-Kung Lin, Chia-Wei Liou, Ching-Yi Lin, Pei-Wen Wang
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2018/7514383

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