Ghrelin, MicroRNAs, and Critical Limb Ischemia: Hungering for a Novel Treatment Option

Ghrelin, MicroRNAs, and Critical Limb Ischemia: Hungering for a Novel Treatment Option

Critical limb ischemia (CLI) is the most severe manifestation of peripheral artery disease. It is characterized by chronic pain at rest, skin ulcerations, and gangrene tissue loss. CLI is a highly morbid condition, resulting in a severely diminished quality of life and a significant risk of mortalit...

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Bibliographic Details
Main Authors: Joshua P. H. Neale, James T. Pearson, Rajesh Katare, Daryl O. Schwenke
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Endocrinology
Subjects:
critical limb ischemia
peripheral artery disease
ghrelin
microRNAs
angiogenesis
regeneration
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00350/full

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