Age-Dependent Risks of Incidence and Mortality of COVID-19 in Hubei Province and Other Parts of China

The new coronavirus SARS-CoV-2 pandemic of early 2020 poses an enormous challenge to global public health. Coronavirus Disease 2019 (COVID-19) caused by the virus has spread rapidly throughout the world, taking thousands of lives in just over 2 months. It is critical to refine the incidence and mort...

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Main Authors: Hongdou Li, Shuang Wang, Fan Zhong, Wuyin Bao, Yipeng Li, Lei Liu, Hongyan Wang, Yungang He
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00190/full
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spelling doaj-8b9fd8d0c25147e786aac40b9dfd19bc2020-11-25T02:37:49ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2020-04-01710.3389/fmed.2020.00190540532Age-Dependent Risks of Incidence and Mortality of COVID-19 in Hubei Province and Other Parts of ChinaHongdou Li0Hongdou Li1Hongdou Li2Shuang Wang3Fan Zhong4Fan Zhong5Wuyin Bao6Yipeng Li7Lei Liu8Lei Liu9Hongyan Wang10Yungang He11Yungang He12Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, ChinaInternational Co-laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai, ChinaThe Institute of Reproduction and Developmental Biology, Obstetrics Gynecology Hospital, Fudan University, Shanghai, ChinaGuanghan Research Center of Personalized Healthcare, Shanghai, ChinaShanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, ChinaInternational Co-laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai, ChinaGuanghan Research Center of Personalized Healthcare, Shanghai, ChinaGuanghan Research Center of Personalized Healthcare, Shanghai, ChinaShanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, ChinaInternational Co-laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai, ChinaThe Institute of Reproduction and Developmental Biology, Obstetrics Gynecology Hospital, Fudan University, Shanghai, ChinaShanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, ChinaInternational Co-laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai, ChinaThe new coronavirus SARS-CoV-2 pandemic of early 2020 poses an enormous challenge to global public health. Coronavirus Disease 2019 (COVID-19) caused by the virus has spread rapidly throughout the world, taking thousands of lives in just over 2 months. It is critical to refine the incidence and mortality risks of COVID-19 for the effective management of the general public and patients during the outbreak. In this report, we investigate the incidence and mortality risks of the infection by analyzing the age composition of 5,319 infected patients, 76 fatal cases, and 1,144,648 individuals of the general public in China. Our results show a relatively low incidence risk for young people but a very high mortality risk for seniors. Notably, mortality risk could be as high as 0.48 for people older than 80 years. Furthermore, our study suggests that a good medical service can effectively reduce the mortality rate of the viral infection to 1% or less.https://www.frontiersin.org/article/10.3389/fmed.2020.00190/fullcoronavirusSARS-CoV-2COVID-19incidence riskmortality risk
collection DOAJ
language English
format Article
sources DOAJ
author Hongdou Li
Hongdou Li
Hongdou Li
Shuang Wang
Fan Zhong
Fan Zhong
Wuyin Bao
Yipeng Li
Lei Liu
Lei Liu
Hongyan Wang
Yungang He
Yungang He
spellingShingle Hongdou Li
Hongdou Li
Hongdou Li
Shuang Wang
Fan Zhong
Fan Zhong
Wuyin Bao
Yipeng Li
Lei Liu
Lei Liu
Hongyan Wang
Yungang He
Yungang He
Age-Dependent Risks of Incidence and Mortality of COVID-19 in Hubei Province and Other Parts of China
Frontiers in Medicine
coronavirus
SARS-CoV-2
COVID-19
incidence risk
mortality risk
author_facet Hongdou Li
Hongdou Li
Hongdou Li
Shuang Wang
Fan Zhong
Fan Zhong
Wuyin Bao
Yipeng Li
Lei Liu
Lei Liu
Hongyan Wang
Yungang He
Yungang He
author_sort Hongdou Li
title Age-Dependent Risks of Incidence and Mortality of COVID-19 in Hubei Province and Other Parts of China
title_short Age-Dependent Risks of Incidence and Mortality of COVID-19 in Hubei Province and Other Parts of China
title_full Age-Dependent Risks of Incidence and Mortality of COVID-19 in Hubei Province and Other Parts of China
title_fullStr Age-Dependent Risks of Incidence and Mortality of COVID-19 in Hubei Province and Other Parts of China
title_full_unstemmed Age-Dependent Risks of Incidence and Mortality of COVID-19 in Hubei Province and Other Parts of China
title_sort age-dependent risks of incidence and mortality of covid-19 in hubei province and other parts of china
publisher Frontiers Media S.A.
series Frontiers in Medicine
issn 2296-858X
publishDate 2020-04-01
description The new coronavirus SARS-CoV-2 pandemic of early 2020 poses an enormous challenge to global public health. Coronavirus Disease 2019 (COVID-19) caused by the virus has spread rapidly throughout the world, taking thousands of lives in just over 2 months. It is critical to refine the incidence and mortality risks of COVID-19 for the effective management of the general public and patients during the outbreak. In this report, we investigate the incidence and mortality risks of the infection by analyzing the age composition of 5,319 infected patients, 76 fatal cases, and 1,144,648 individuals of the general public in China. Our results show a relatively low incidence risk for young people but a very high mortality risk for seniors. Notably, mortality risk could be as high as 0.48 for people older than 80 years. Furthermore, our study suggests that a good medical service can effectively reduce the mortality rate of the viral infection to 1% or less.
topic coronavirus
SARS-CoV-2
COVID-19
incidence risk
mortality risk
url https://www.frontiersin.org/article/10.3389/fmed.2020.00190/full
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