Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
This work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing...
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doaj-8ba585b7e1f4478a882da44e8c19c1562020-11-25T03:23:02ZengElsevierGenomics Data2213-59602016-12-0110C515310.1016/j.gdata.2016.09.002Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitroSumantra Chatterjee0Petra Kraus1V. Sivakamasundari2Sook Peng Yap3Vibhor Kumar4Shyam Prabhakar5Thomas Lufkin6McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N. Broadway, Baltimore, MD 21205, USADepartment of Biology, Clarkson University, 8 Clarkson Avenue, Potsdam, NY 13699, USAThe Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06030, USAApta Biosciences, 31 Biopolis Way, Nanos, Singapore 138669, SingaporeGenome Institute of Singapore, 60 Biopolis Street, Singapore 138672, SingaporeGenome Institute of Singapore, 60 Biopolis Street, Singapore 138672, SingaporeDepartment of Biology, Clarkson University, 8 Clarkson Avenue, Potsdam, NY 13699, USAThis work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing cell type specification and the generation of tissues and subsequent organs [1]. Our earlier work identified the role of the DNA-binding homeodomain containing protein Bapx1/Nkx3.2 in midgestation murine embryos. Microarray analysis of EGFP-tagged cells (both wildtype and null) was integrated using ChIP-Seq analysis of Bapx1/Nkx3.2 and Sox9 DNA-binding proteins in living tissue.http://www.sciencedirect.com/science/article/pii/S2213596016301167Genome bindingBapx1MouseChIP-SeqOccupancy profiling by NGS |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sumantra Chatterjee Petra Kraus V. Sivakamasundari Sook Peng Yap Vibhor Kumar Shyam Prabhakar Thomas Lufkin |
spellingShingle |
Sumantra Chatterjee Petra Kraus V. Sivakamasundari Sook Peng Yap Vibhor Kumar Shyam Prabhakar Thomas Lufkin Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro Genomics Data Genome binding Bapx1 Mouse ChIP-Seq Occupancy profiling by NGS |
author_facet |
Sumantra Chatterjee Petra Kraus V. Sivakamasundari Sook Peng Yap Vibhor Kumar Shyam Prabhakar Thomas Lufkin |
author_sort |
Sumantra Chatterjee |
title |
Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro |
title_short |
Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro |
title_full |
Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro |
title_fullStr |
Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro |
title_full_unstemmed |
Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro |
title_sort |
genome wide binding (chip-seq) of murine bapx1 and sox9 proteins in vivo and in vitro |
publisher |
Elsevier |
series |
Genomics Data |
issn |
2213-5960 |
publishDate |
2016-12-01 |
description |
This work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing cell type specification and the generation of tissues and subsequent organs [1]. Our earlier work identified the role of the DNA-binding homeodomain containing protein Bapx1/Nkx3.2 in midgestation murine embryos. Microarray analysis of EGFP-tagged cells (both wildtype and null) was integrated using ChIP-Seq analysis of Bapx1/Nkx3.2 and Sox9 DNA-binding proteins in living tissue. |
topic |
Genome binding Bapx1 Mouse ChIP-Seq Occupancy profiling by NGS |
url |
http://www.sciencedirect.com/science/article/pii/S2213596016301167 |
work_keys_str_mv |
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