Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro

This work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing...

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Main Authors: Sumantra Chatterjee, Petra Kraus, V. Sivakamasundari, Sook Peng Yap, Vibhor Kumar, Shyam Prabhakar, Thomas Lufkin
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Genomics Data
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596016301167
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spelling doaj-8ba585b7e1f4478a882da44e8c19c1562020-11-25T03:23:02ZengElsevierGenomics Data2213-59602016-12-0110C515310.1016/j.gdata.2016.09.002Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitroSumantra Chatterjee0Petra Kraus1V. Sivakamasundari2Sook Peng Yap3Vibhor Kumar4Shyam Prabhakar5Thomas Lufkin6McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N. Broadway, Baltimore, MD 21205, USADepartment of Biology, Clarkson University, 8 Clarkson Avenue, Potsdam, NY 13699, USAThe Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06030, USAApta Biosciences, 31 Biopolis Way, Nanos, Singapore 138669, SingaporeGenome Institute of Singapore, 60 Biopolis Street, Singapore 138672, SingaporeGenome Institute of Singapore, 60 Biopolis Street, Singapore 138672, SingaporeDepartment of Biology, Clarkson University, 8 Clarkson Avenue, Potsdam, NY 13699, USAThis work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing cell type specification and the generation of tissues and subsequent organs [1]. Our earlier work identified the role of the DNA-binding homeodomain containing protein Bapx1/Nkx3.2 in midgestation murine embryos. Microarray analysis of EGFP-tagged cells (both wildtype and null) was integrated using ChIP-Seq analysis of Bapx1/Nkx3.2 and Sox9 DNA-binding proteins in living tissue.http://www.sciencedirect.com/science/article/pii/S2213596016301167Genome bindingBapx1MouseChIP-SeqOccupancy profiling by NGS
collection DOAJ
language English
format Article
sources DOAJ
author Sumantra Chatterjee
Petra Kraus
V. Sivakamasundari
Sook Peng Yap
Vibhor Kumar
Shyam Prabhakar
Thomas Lufkin
spellingShingle Sumantra Chatterjee
Petra Kraus
V. Sivakamasundari
Sook Peng Yap
Vibhor Kumar
Shyam Prabhakar
Thomas Lufkin
Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
Genomics Data
Genome binding
Bapx1
Mouse
ChIP-Seq
Occupancy profiling by NGS
author_facet Sumantra Chatterjee
Petra Kraus
V. Sivakamasundari
Sook Peng Yap
Vibhor Kumar
Shyam Prabhakar
Thomas Lufkin
author_sort Sumantra Chatterjee
title Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title_short Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title_full Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title_fullStr Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title_full_unstemmed Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
title_sort genome wide binding (chip-seq) of murine bapx1 and sox9 proteins in vivo and in vitro
publisher Elsevier
series Genomics Data
issn 2213-5960
publishDate 2016-12-01
description This work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing cell type specification and the generation of tissues and subsequent organs [1]. Our earlier work identified the role of the DNA-binding homeodomain containing protein Bapx1/Nkx3.2 in midgestation murine embryos. Microarray analysis of EGFP-tagged cells (both wildtype and null) was integrated using ChIP-Seq analysis of Bapx1/Nkx3.2 and Sox9 DNA-binding proteins in living tissue.
topic Genome binding
Bapx1
Mouse
ChIP-Seq
Occupancy profiling by NGS
url http://www.sciencedirect.com/science/article/pii/S2213596016301167
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