CUT&Tag for efficient epigenomic profiling of small samples and single cells

CUT&Tag for efficient epigenomic profiling of small samples and single cells

Understanding gene regulation will require mapping specific chromain features in a small number of cells at high resolution. Here the authors describe CUT&Tag, which uses antibody-mediated tethering of Tn5 transposase to a chromatin protein to generate high resolution libraries.

Bibliographic Details
Main Authors: Hatice S. Kaya-Okur, Steven J. Wu, Christine A. Codomo, Erica S. Pledger, Terri D. Bryson, Jorja G. Henikoff, Kami Ahmad, Steven Henikoff
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09982-5

Internet

https://doi.org/10.1038/s41467-019-09982-5

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