Surgical Treatment for Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is an epithelial tumor derived from hepatocytes; it accounts for 80% of all primary liver cancers and ranks globally as the fourth leading cause of cancer-related deaths. HCC treatment is a multidisciplinary and a multimodal task, with surgery in the form of liver rese...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2015-01-01
|
Series: | The Saudi Journal of Gastroenterology |
Subjects: | |
Online Access: | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2015;volume=21;issue=1;spage=11;epage=17;aulast=Madkhali |
id |
doaj-8bd44d3a823f4631ac1931cd5d939419 |
---|---|
record_format |
Article |
spelling |
doaj-8bd44d3a823f4631ac1931cd5d9394192020-11-25T02:12:51ZengWolters Kluwer Medknow PublicationsThe Saudi Journal of Gastroenterology1319-37671998-40492015-01-01211111710.4103/1319-3767.151216Surgical Treatment for Hepatocellular CarcinomaAhmad A MadkhaliZahir T FadelMurad M AljiffryMazen M HassanainHepatocellular carcinoma (HCC) is an epithelial tumor derived from hepatocytes; it accounts for 80% of all primary liver cancers and ranks globally as the fourth leading cause of cancer-related deaths. HCC treatment is a multidisciplinary and a multimodal task, with surgery in the form of liver resection and liver transplantation (LT) representing the only potentially curative modality. However, there are variable opinions and discussions about applying these surgical options and using other supporting treatments. This article is a narrative review that includes articles published from 1984 to 2013 located by searching scientific databases such as PubMed, SCOPUS, and Elsevier, with the main keyword of hepatocellular carcinoma in addition to other keywords such as liver transplantation, liver resection, transarterial chemoembolization, portal vein embolization, bridging therapy, and downstaging. In this review, we focus mainly on the surgical treatment options offered for HCC, in order to illustrate the current relevant data available in the literature to help in applying these surgical options and to use other supporting treatment modalities when appropriate.http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2015;volume=21;issue=1;spage=11;epage=17;aulast=MadkhaliBridging therapydownsizinghepatocellular carcinomaliverliver malignant tumorliver transplantationliver resectiontransarterial chemoembolization |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ahmad A Madkhali Zahir T Fadel Murad M Aljiffry Mazen M Hassanain |
spellingShingle |
Ahmad A Madkhali Zahir T Fadel Murad M Aljiffry Mazen M Hassanain Surgical Treatment for Hepatocellular Carcinoma The Saudi Journal of Gastroenterology Bridging therapy downsizing hepatocellular carcinoma liver liver malignant tumor liver transplantation liver resection transarterial chemoembolization |
author_facet |
Ahmad A Madkhali Zahir T Fadel Murad M Aljiffry Mazen M Hassanain |
author_sort |
Ahmad A Madkhali |
title |
Surgical Treatment for Hepatocellular Carcinoma |
title_short |
Surgical Treatment for Hepatocellular Carcinoma |
title_full |
Surgical Treatment for Hepatocellular Carcinoma |
title_fullStr |
Surgical Treatment for Hepatocellular Carcinoma |
title_full_unstemmed |
Surgical Treatment for Hepatocellular Carcinoma |
title_sort |
surgical treatment for hepatocellular carcinoma |
publisher |
Wolters Kluwer Medknow Publications |
series |
The Saudi Journal of Gastroenterology |
issn |
1319-3767 1998-4049 |
publishDate |
2015-01-01 |
description |
Hepatocellular carcinoma (HCC) is an epithelial tumor derived from hepatocytes; it accounts for 80% of all primary liver cancers and ranks globally as the fourth leading cause of cancer-related deaths. HCC treatment is a multidisciplinary and a multimodal task, with surgery in the form of liver resection and liver transplantation (LT) representing the only potentially curative modality. However, there are variable opinions and discussions about applying these surgical options and using other supporting treatments. This article is a narrative review that includes articles published from 1984 to 2013 located by searching scientific databases such as PubMed, SCOPUS, and Elsevier, with the main keyword of hepatocellular carcinoma in addition to other keywords such as liver transplantation, liver resection, transarterial chemoembolization, portal vein embolization, bridging therapy, and downstaging. In this review, we focus mainly on the surgical treatment options offered for HCC, in order to illustrate the current relevant data available in the literature to help in applying these surgical options and to use other supporting treatment modalities when appropriate. |
topic |
Bridging therapy downsizing hepatocellular carcinoma liver liver malignant tumor liver transplantation liver resection transarterial chemoembolization |
url |
http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2015;volume=21;issue=1;spage=11;epage=17;aulast=Madkhali |
work_keys_str_mv |
AT ahmadamadkhali surgicaltreatmentforhepatocellularcarcinoma AT zahirtfadel surgicaltreatmentforhepatocellularcarcinoma AT muradmaljiffry surgicaltreatmentforhepatocellularcarcinoma AT mazenmhassanain surgicaltreatmentforhepatocellularcarcinoma |
_version_ |
1724907819440799744 |