Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?

Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?

Abstract Background Exosomes isolated from plasma of patients with sepsis may induce vascular apoptosis and myocardial dysfunction by mechanisms related to inflammation and oxidative stress. Despite previous studies demonstrating that these vesicles contain genetic material related to cellular commu...

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Bibliographic Details
Main Authors: Juliana Monte Real, Ludmila Rodrigues Pinto Ferreira, Gustavo Henrique Esteves, Fernanda Christtanini Koyama, Marcos Vinícius Salles Dias, João Evangelista Bezerra-Neto, Edécio Cunha-Neto, Flavia Ribeiro Machado, Reinaldo Salomão, Luciano Cesar Pontes Azevedo
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Critical Care
Subjects:
Sepsis
Extracellular vesicles
Exosomes
MicroRNAs
Messenger RNA
Inflammatory response
Online Access:http://link.springer.com/article/10.1186/s13054-018-2003-3

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http://link.springer.com/article/10.1186/s13054-018-2003-3

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