Cellular Mechanisms of Human Atherogenesis: Focus on Chronification of Inflammation and Mitochondrial Mutations

Cellular Mechanisms of Human Atherogenesis: Focus on Chronification of Inflammation and Mitochondrial Mutations

Atherosclerosis is one of the most common diseases of the cardiovascular system that leads to the development of life-threatening conditions, such as heart attack and stroke. Arthrosclerosis affects various arteries in the human body, but is especially dangerous in the arteries alimenting heart and...

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Bibliographic Details
Main Authors: Alexander M. Markin, Igor A. Sobenin, Andrey V. Grechko, Dongwei Zhang, Alexander N. Orekhov
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
atherosclerosis
nuclear genome
mitochondria
mutations
inflammation
mtDNA
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00642/full

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