Familial Myelodysplastic/Acute Leukemia Syndromes—Myeloid Neoplasms with Germline Predisposition

Familial Myelodysplastic/Acute Leukemia Syndromes—Myeloid Neoplasms with Germline Predisposition

Although most cases of myeloid neoplasms are sporadic, a small subset has been associated with germline mutations. The 2016 revision of the World Health Organization classification included these cases in a myeloid neoplasm group with a predisposing germline mutational background. These patients mus...

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Bibliographic Details
Main Authors: Renata Lyrio Rafael Baptista, Anna Cláudia Evangelista dos Santos, Luciana Mayumi Gutiyama, Cristiana Solza, Ilana Renault Zalcberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Oncology
Subjects:
familial
leukemia
myeloid neoplasms
germline mutations
WHO classification
GATA2
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00206/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2017.00206/full

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