Fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997–2007: A longitudinal study
Objective: A recent longitudinal study reported an association between fine particulate (PM2.5) exposure and preterm birth (PTB) in a US cohort. We applied the same design to an Australian cohort to investigate associations with PTB and pre-labor rupture of membranes (PROM). Methods: From 287,680 bi...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2014-12-01
|
Series: | Environment International |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412014002359 |
id |
doaj-8bf45ed650934e7da3d9e2245f7a6595 |
---|---|
record_format |
Article |
spelling |
doaj-8bf45ed650934e7da3d9e2245f7a65952020-11-25T00:40:51ZengElsevierEnvironment International0160-41202014-12-0173143149Fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997–2007: A longitudinal studyGavin Pereira0Michelle L. Bell1Kathleen Belanger2Nicholas de Klerk3Telethon Kids Institute, The University of Western Australia, 100 Roberts Road, Subiaco, WA 6008, Australia; Center for Perinatal Pediatric and Environmental Epidemiology, School of Medicine, Yale University, New Haven, CT, United States; Corresponding author at: Telethon Kids Institute, The University of Western Australia, 100 Roberts Road, Subiaco, WA 6008, Australia. Tel.: +1 203 764 9767.Center for Perinatal Pediatric and Environmental Epidemiology, School of Medicine, Yale University, New Haven, CT, United States; School of Forestry and Environmental Studies, Yale University, New Haven, CT, United StatesCenter for Perinatal Pediatric and Environmental Epidemiology, School of Medicine, Yale University, New Haven, CT, United StatesTelethon Kids Institute, The University of Western Australia, 100 Roberts Road, Subiaco, WA 6008, AustraliaObjective: A recent longitudinal study reported an association between fine particulate (PM2.5) exposure and preterm birth (PTB) in a US cohort. We applied the same design to an Australian cohort to investigate associations with PTB and pre-labor rupture of membranes (PROM). Methods: From 287,680 births, we selected 39,189 women who had singleton births at least twice in Western Australia in 1997–2007 (n = 86,844 births). Analyses matched pregnancies to the same women with conditional logistic regression. Results: For PROM adjusted odds ratios (ORs) for a 1 μg/m3 increase in PM2.5 in the first trimester, second trimester, third trimester, and whole pregnancy were 1.00 (95% confidence interval (CI): 0.97, 1.03), 1.03 (95% CI: 1.00, 1.06), 1.02 (95% CI: 1.00, 1.05), and 1.02 (95% CI: 0.99, 1.05) respectively. For PTB, corresponding ORs were 1.00 (95% CI: 0.96, 1.04), 1.00 (95% CI: 0.96, 1.04), 0.98 (95% CI: 0.94, 1.02), and 0.99 (95% CI: 0.95, 1.04) respectively. Conclusion: Risk of PROM was greater for pregnancies with elevated PM2.5 exposure in the second trimester than were other pregnancies to the same Australian women at lower exposure. There was insufficient evidence for an association with PTB, indicating that a longer time period might be needed to observe an association if a causal effect exists. Keywords: Preterm birth, Particulate matter, Longitudinal study, Pre-labor rupture of membranes, Pregnancy outcomeshttp://www.sciencedirect.com/science/article/pii/S0160412014002359 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Gavin Pereira Michelle L. Bell Kathleen Belanger Nicholas de Klerk |
spellingShingle |
Gavin Pereira Michelle L. Bell Kathleen Belanger Nicholas de Klerk Fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997–2007: A longitudinal study Environment International |
author_facet |
Gavin Pereira Michelle L. Bell Kathleen Belanger Nicholas de Klerk |
author_sort |
Gavin Pereira |
title |
Fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997–2007: A longitudinal study |
title_short |
Fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997–2007: A longitudinal study |
title_full |
Fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997–2007: A longitudinal study |
title_fullStr |
Fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997–2007: A longitudinal study |
title_full_unstemmed |
Fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997–2007: A longitudinal study |
title_sort |
fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in perth, western australia 1997–2007: a longitudinal study |
publisher |
Elsevier |
series |
Environment International |
issn |
0160-4120 |
publishDate |
2014-12-01 |
description |
Objective: A recent longitudinal study reported an association between fine particulate (PM2.5) exposure and preterm birth (PTB) in a US cohort. We applied the same design to an Australian cohort to investigate associations with PTB and pre-labor rupture of membranes (PROM). Methods: From 287,680 births, we selected 39,189 women who had singleton births at least twice in Western Australia in 1997–2007 (n = 86,844 births). Analyses matched pregnancies to the same women with conditional logistic regression. Results: For PROM adjusted odds ratios (ORs) for a 1 μg/m3 increase in PM2.5 in the first trimester, second trimester, third trimester, and whole pregnancy were 1.00 (95% confidence interval (CI): 0.97, 1.03), 1.03 (95% CI: 1.00, 1.06), 1.02 (95% CI: 1.00, 1.05), and 1.02 (95% CI: 0.99, 1.05) respectively. For PTB, corresponding ORs were 1.00 (95% CI: 0.96, 1.04), 1.00 (95% CI: 0.96, 1.04), 0.98 (95% CI: 0.94, 1.02), and 0.99 (95% CI: 0.95, 1.04) respectively. Conclusion: Risk of PROM was greater for pregnancies with elevated PM2.5 exposure in the second trimester than were other pregnancies to the same Australian women at lower exposure. There was insufficient evidence for an association with PTB, indicating that a longer time period might be needed to observe an association if a causal effect exists. Keywords: Preterm birth, Particulate matter, Longitudinal study, Pre-labor rupture of membranes, Pregnancy outcomes |
url |
http://www.sciencedirect.com/science/article/pii/S0160412014002359 |
work_keys_str_mv |
AT gavinpereira fineparticulatematterandriskofpretermbirthandprelaborruptureofmembranesinperthwesternaustralia19972007alongitudinalstudy AT michellelbell fineparticulatematterandriskofpretermbirthandprelaborruptureofmembranesinperthwesternaustralia19972007alongitudinalstudy AT kathleenbelanger fineparticulatematterandriskofpretermbirthandprelaborruptureofmembranesinperthwesternaustralia19972007alongitudinalstudy AT nicholasdeklerk fineparticulatematterandriskofpretermbirthandprelaborruptureofmembranesinperthwesternaustralia19972007alongitudinalstudy |
_version_ |
1725288404938129408 |