EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer

EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer

Abstract Background Epidermal growth factor receptor (EGFR), a well-known oncogenic driver, contributes to the initiation and progression of a wide range of cancer types. Aberrant lipid metabolism including highly produced monounsaturated fatty acids (MUFA) is recognized as a hallmark of cancer. How...

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Bibliographic Details
Main Authors: Jiqin Zhang, Fei Song, Xiaojing Zhao, Hua Jiang, Xiuqi Wu, Biao Wang, Min Zhou, Mi Tian, Bizhi Shi, Huamao Wang, Yuanhui Jia, Hai Wang, Xiaorong Pan, Zonghai Li
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Molecular Cancer
Online Access:http://link.springer.com/article/10.1186/s12943-017-0704-x

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