Mechanisms by Which Kinesin-5 Motors Perform Their Multiple Intracellular Functions

Mechanisms by Which Kinesin-5 Motors Perform Their Multiple Intracellular Functions

Bipolar kinesin-5 motor proteins perform multiple intracellular functions, mainly during mitotic cell division. Their specialized structural characteristics enable these motors to perform their essential functions by crosslinking and sliding apart antiparallel microtubules (MTs). In this review, we...

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Bibliographic Details
Main Authors: Himanshu Pandey, Mary Popov, Alina Goldstein-Levitin, Larisa Gheber
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
kinesin-5
microtubules
mitosis
cell-cycle regulation of kinesin activity
Online Access:https://www.mdpi.com/1422-0067/22/12/6420

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