DEPTOR maintains plasma cell differentiation and favorably affects prognosis in multiple myeloma

DEPTOR maintains plasma cell differentiation and favorably affects prognosis in multiple myeloma

Abstract Background The B cell maturation process involves multiple steps, which are controlled by relevant pathways and transcription factors. The understanding of the final stages of plasma cell (PC) differentiation could provide new insights for therapeutic strategies in multiple myeloma (MM). He...

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Bibliographic Details
Main Authors: Dalia Quwaider, Luis A. Corchete, Irena Misiewicz-Krzeminska, María E. Sarasquete, José J. Pérez, Patryk Krzeminski, Noemí Puig, María Victoria Mateos, Ramón García-Sanz, Ana B. Herrero, Norma C. Gutiérrez
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Hematology & Oncology
Subjects:
DEPTOR
Multiple myeloma
Plasma cell development
B lymphocyte differentiation
miRNAs
Online Access:http://link.springer.com/article/10.1186/s13045-017-0461-8

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