ATP Production Relies on Fatty Acid Oxidation Rather than Glycolysis in Pancreatic Ductal Adenocarcinoma

ATP Production Relies on Fatty Acid Oxidation Rather than Glycolysis in Pancreatic Ductal Adenocarcinoma

Glycolysis is known as the main pathway for ATP production in cancer cells. However, in cancer cells, glucose deprivation for 24 h does not reduce ATP levels, whereas it does suppress lactate production. In this study, metabolic pathways were blocked to identify the main pathway of ATP production in...

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Bibliographic Details
Main Authors: Jae-Seon Lee, Su-Jin Oh, Hyun-Jung Choi, Joon Hee Kang, Seon-Hyeong Lee, Ji Sun Ha, Sang Myung Woo, Hyonchol Jang, Ho Lee, Soo-Youl Kim
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
PDAC
glycolysis
fatty acid oxidation
ATP production
KC mouse
Online Access:https://www.mdpi.com/2072-6694/12/9/2477

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