A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects
A simple and efficient strategy for the synthesis of 1-ethynylcyclohex-2-enol derivatives was developed utilizing regioselective addition of acetylides to enediones based on steric effects. Further investigation of the substrate scope of enediones indicated that all the addition reactions ocurred in...
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2013-09-01
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Series: | Molecules |
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Online Access: | http://www.mdpi.com/1420-3049/18/9/10776 |
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doaj-8c270f022aee422692f61ccf7f505d642020-11-24T22:09:17ZengMDPI AGMolecules1420-30492013-09-01189107761078810.3390/molecules180910776A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric EffectsZhaohai QinYumei XiaoShijie DuXiaoyong YuanDongyan YangChuan WanXiaoqiang HanA simple and efficient strategy for the synthesis of 1-ethynylcyclohex-2-enol derivatives was developed utilizing regioselective addition of acetylides to enediones based on steric effects. Further investigation of the substrate scope of enediones indicated that all the addition reactions ocurred in good yield.http://www.mdpi.com/1420-3049/18/9/10776regioselective additionacetylidesenedionessteric effects1-ethynylcyclohex-2-enol derivatives |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zhaohai Qin Yumei Xiao Shijie Du Xiaoyong Yuan Dongyan Yang Chuan Wan Xiaoqiang Han |
spellingShingle |
Zhaohai Qin Yumei Xiao Shijie Du Xiaoyong Yuan Dongyan Yang Chuan Wan Xiaoqiang Han A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects Molecules regioselective addition acetylides enediones steric effects 1-ethynylcyclohex-2-enol derivatives |
author_facet |
Zhaohai Qin Yumei Xiao Shijie Du Xiaoyong Yuan Dongyan Yang Chuan Wan Xiaoqiang Han |
author_sort |
Zhaohai Qin |
title |
A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects |
title_short |
A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects |
title_full |
A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects |
title_fullStr |
A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects |
title_full_unstemmed |
A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects |
title_sort |
highly efficient regioselective addition of acetylides to enediones based on steric effects |
publisher |
MDPI AG |
series |
Molecules |
issn |
1420-3049 |
publishDate |
2013-09-01 |
description |
A simple and efficient strategy for the synthesis of 1-ethynylcyclohex-2-enol derivatives was developed utilizing regioselective addition of acetylides to enediones based on steric effects. Further investigation of the substrate scope of enediones indicated that all the addition reactions ocurred in good yield. |
topic |
regioselective addition acetylides enediones steric effects 1-ethynylcyclohex-2-enol derivatives |
url |
http://www.mdpi.com/1420-3049/18/9/10776 |
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