A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects

A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects

A simple and efficient strategy for the synthesis of 1-ethynylcyclohex-2-enol derivatives was developed utilizing regioselective addition of acetylides to enediones based on steric effects. Further investigation of the substrate scope of enediones indicated that all the addition reactions ocurred in...

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Main Authors: Zhaohai Qin, Yumei Xiao, Shijie Du, Xiaoyong Yuan, Dongyan Yang, Chuan Wan, Xiaoqiang Han
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Molecules
Subjects:
regioselective addition
acetylides
enediones
steric effects
1-ethynylcyclohex-2-enol derivatives
Online Access:http://www.mdpi.com/1420-3049/18/9/10776
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spelling doaj-8c270f022aee422692f61ccf7f505d642020-11-24T22:09:17ZengMDPI AGMolecules1420-30492013-09-01189107761078810.3390/molecules180910776A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric EffectsZhaohai QinYumei XiaoShijie DuXiaoyong YuanDongyan YangChuan WanXiaoqiang HanA simple and efficient strategy for the synthesis of 1-ethynylcyclohex-2-enol derivatives was developed utilizing regioselective addition of acetylides to enediones based on steric effects. Further investigation of the substrate scope of enediones indicated that all the addition reactions ocurred in good yield.http://www.mdpi.com/1420-3049/18/9/10776regioselective additionacetylidesenedionessteric effects1-ethynylcyclohex-2-enol derivatives
collection DOAJ
language English
format Article
sources DOAJ
author Zhaohai Qin
Yumei Xiao
Shijie Du
Xiaoyong Yuan
Dongyan Yang
Chuan Wan
Xiaoqiang Han
spellingShingle Zhaohai Qin
Yumei Xiao
Shijie Du
Xiaoyong Yuan
Dongyan Yang
Chuan Wan
Xiaoqiang Han
A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects
Molecules
regioselective addition
acetylides
enediones
steric effects
1-ethynylcyclohex-2-enol derivatives
author_facet Zhaohai Qin
Yumei Xiao
Shijie Du
Xiaoyong Yuan
Dongyan Yang
Chuan Wan
Xiaoqiang Han
author_sort Zhaohai Qin
title A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects
title_short A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects
title_full A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects
title_fullStr A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects
title_full_unstemmed A Highly Efficient Regioselective Addition of Acetylides to Enediones Based on Steric Effects
title_sort highly efficient regioselective addition of acetylides to enediones based on steric effects
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2013-09-01
description A simple and efficient strategy for the synthesis of 1-ethynylcyclohex-2-enol derivatives was developed utilizing regioselective addition of acetylides to enediones based on steric effects. Further investigation of the substrate scope of enediones indicated that all the addition reactions ocurred in good yield.
topic regioselective addition
acetylides
enediones
steric effects
1-ethynylcyclohex-2-enol derivatives
url http://www.mdpi.com/1420-3049/18/9/10776
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