Targeting NLRP3 Inflammasome Activation in Severe Asthma

Targeting NLRP3 Inflammasome Activation in Severe Asthma

Severe asthma (SA) is a chronic lung disease characterized by recurring symptoms of reversible airflow obstruction, airway hyper-responsiveness (AHR), and inflammation that is resistant to currently employed treatments. The nucleotide-binding oligomerization domain-like Receptor Family Pyrin Domain...

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Bibliographic Details
Main Authors: Efthymia Theofani, Maria Semitekolou, Ioannis Morianos, Konstantinos Samitas, Georgina Xanthou
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Journal of Clinical Medicine
Subjects:
severe asthma
innate immunity
immune regulation
nlrp3
il-1β
allergic airway inflammation
Online Access:https://www.mdpi.com/2077-0383/8/10/1615

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