Proteophosophoglycans regurgitated by Leishmania-infected sand flies target the L-arginine metabolism of host macrophages to promote parasite survival.
All natural Leishmania infections start in the skin; however, little is known of the contribution made by the sand fly vector to the earliest events in mammalian infection, especially in inflamed skin that can rapidly kill invading parasites. During transmission sand flies regurgitate a proteophosph...
Main Authors: | Matthew Rogers, Pascale Kropf, Beak-San Choi, Rod Dillon, Maria Podinovskaia, Paul Bates, Ingrid Müller |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-08-01
|
Series: | PLoS Pathogens |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19696894/?tool=EBI |
Similar Items
-
Leishmania proteophosphoglycans regurgitated from infected sand flies accelerate dermal wound repair and exacerbate leishmaniasis via insulin-like growth factor 1-dependent signalling.
by: Emilie Giraud, et al.
Published: (2018-01-01) -
Leishmania manipulation of sand fly feeding behavior results in enhanced transmission.
by: Matthew E Rogers, et al.
Published: (2007-06-01) -
Development of Leishmania Parasite in Interaction with Sand Fly Vectors of Leishmaniasis
by: Nasibeh Hosseini-Vasoukolaei, et al.
Published: (2018-09-01) -
<it>Leishmania</it> development in sand flies: parasite-vector interactions overview
by: Dostálová Anna, et al.
Published: (2012-12-01) -
Leishmania and sand flies
by: Paul Williams
Published: (1988-11-01)