Osteoblast-Derived Paracrine and Juxtacrine Signals Protect Disseminated Breast Cancer Cells from Stress

Osteoblast-Derived Paracrine and Juxtacrine Signals Protect Disseminated Breast Cancer Cells from Stress

Metastatic breast cancer in bone is incurable and there is an urgent need to develop new therapeutic approaches to improve survival. Key to this is understanding the mechanisms governing cancer cell survival and growth in bone, which involves interplay between malignant and accessory cell types. Her...

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Bibliographic Details
Main Authors: Russell Hughes, Xinyue Chen, Natasha Cowley, Penelope D. Ottewell, Rhoda J. Hawkins, Keith D. Hunter, Jamie K. Hobbs, Nicola J. Brown, Ingunn Holen
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
skeletal
metastasis
dormancy
latency
breast cancer
Online Access:https://www.mdpi.com/2072-6694/13/6/1366

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