Squalene Emulsions for Parenteral Vaccine and Drug Delivery
Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented. Moreover, the physicochemical and biological properties of squalene-containing em...
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| Format: | Article |
| Language: | English |
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MDPI AG
2009-09-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/14/9/3286/ |
| Summary: | Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented. Moreover, the physicochemical and biological properties of squalene-containing emulsions are evaluated in the context of parenteral formulations. Historical and current parenteral emulsion products containing squalene or squalane are discussed. The safety of squalene-based products is also addressed. Finally, analytica techniques for characterization of squalene emulsions are examined. |
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| ISSN: | 1420-3049 |