Squalene Emulsions for Parenteral Vaccine and Drug Delivery

Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented. Moreover, the physicochemical and biological properties of squalene-containing em...

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Bibliographic Details
Main Author:	Christopher B. Fox
Format:	Article
Language:	English
Published:	MDPI AG 2009-09-01
Series:	Molecules
Subjects:	squalene squalane adjuvant emulsion parenteral
Online Access:	http://www.mdpi.com/1420-3049/14/9/3286/

id	doaj-8c51afbf2c6f42f5a52ea59f21235bb7
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spelling	doaj-8c51afbf2c6f42f5a52ea59f21235bb72020-11-25T00:59:40ZengMDPI AGMolecules1420-30492009-09-011493286331210.3390/molecules14093286Squalene Emulsions for Parenteral Vaccine and Drug DeliveryChristopher B. FoxSqualene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented. Moreover, the physicochemical and biological properties of squalene-containing emulsions are evaluated in the context of parenteral formulations. Historical and current parenteral emulsion products containing squalene or squalane are discussed. The safety of squalene-based products is also addressed. Finally, analytica techniques for characterization of squalene emulsions are examined. http://www.mdpi.com/1420-3049/14/9/3286/squalenesqualaneadjuvantemulsionparenteral
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Christopher B. Fox
spellingShingle	Christopher B. Fox Squalene Emulsions for Parenteral Vaccine and Drug Delivery Molecules squalene squalane adjuvant emulsion parenteral
author_facet	Christopher B. Fox
author_sort	Christopher B. Fox
title	Squalene Emulsions for Parenteral Vaccine and Drug Delivery
title_short	Squalene Emulsions for Parenteral Vaccine and Drug Delivery
title_full	Squalene Emulsions for Parenteral Vaccine and Drug Delivery
title_fullStr	Squalene Emulsions for Parenteral Vaccine and Drug Delivery
title_full_unstemmed	Squalene Emulsions for Parenteral Vaccine and Drug Delivery
title_sort	squalene emulsions for parenteral vaccine and drug delivery
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2009-09-01
description	Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented. Moreover, the physicochemical and biological properties of squalene-containing emulsions are evaluated in the context of parenteral formulations. Historical and current parenteral emulsion products containing squalene or squalane are discussed. The safety of squalene-based products is also addressed. Finally, analytica techniques for characterization of squalene emulsions are examined.
topic	squalene squalane adjuvant emulsion parenteral
url	http://www.mdpi.com/1420-3049/14/9/3286/
work_keys_str_mv	AT christopherbfox squaleneemulsionsforparenteralvaccineanddrugdelivery
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Squalene Emulsions for Parenteral Vaccine and Drug Delivery

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