Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis

Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis

Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR...

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Bibliographic Details
Main Authors: Angèle Gayet-Ageron, Patrice Sednaoui, Stephan Lautenschlager, Tristan Ferry, Laurence Toutous-Trellu, Matthias Cavassini, Fatima Yassir, Begoña Martinez de Tejada, Stéphane Emonet, Christophe Combescure, Jacques Schrenzel, Thomas Perneger
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2015-01-01
Series:Emerging Infectious Diseases
Subjects:
Treponema pallidum
Tp47 protein
sensitivity
specificity
syphilis
PCR
Online Access:https://wwwnc.cdc.gov/eid/article/21/1/14-0790_article
Description
Summary:Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM.
ISSN:1080-6040
1080-6059

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