Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis

Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR...

Full description

Bibliographic Details
Main Authors:	Angèle Gayet-Ageron, Patrice Sednaoui, Stephan Lautenschlager, Tristan Ferry, Laurence Toutous-Trellu, Matthias Cavassini, Fatima Yassir, Begoña Martinez de Tejada, Stéphane Emonet, Christophe Combescure, Jacques Schrenzel, Thomas Perneger
Format:	Article
Language:	English
Published:	Centers for Disease Control and Prevention 2015-01-01
Series:	Emerging Infectious Diseases
Subjects:	Treponema pallidum Tp47 protein sensitivity specificity syphilis PCR
Online Access:	https://wwwnc.cdc.gov/eid/article/21/1/14-0790_article

id	doaj-8c5f9111ff0f4865ae735022196a8d10
record_format	Article
spelling	doaj-8c5f9111ff0f4865ae735022196a8d102020-11-25T02:13:58ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592015-01-0121112712910.3201/eid2101.140790Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary SyphilisAngèle Gayet-AgeronPatrice SednaouiStephan LautenschlagerTristan FerryLaurence Toutous-TrelluMatthias CavassiniFatima YassirBegoña Martinez de TejadaStéphane EmonetChristophe CombescureJacques SchrenzelThomas PernegerTreponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM. https://wwwnc.cdc.gov/eid/article/21/1/14-0790_articleTreponema pallidumTp47 proteinsensitivityspecificitysyphilisPCR
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Angèle Gayet-Ageron Patrice Sednaoui Stephan Lautenschlager Tristan Ferry Laurence Toutous-Trellu Matthias Cavassini Fatima Yassir Begoña Martinez de Tejada Stéphane Emonet Christophe Combescure Jacques Schrenzel Thomas Perneger
spellingShingle	Angèle Gayet-Ageron Patrice Sednaoui Stephan Lautenschlager Tristan Ferry Laurence Toutous-Trellu Matthias Cavassini Fatima Yassir Begoña Martinez de Tejada Stéphane Emonet Christophe Combescure Jacques Schrenzel Thomas Perneger Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis Emerging Infectious Diseases Treponema pallidum Tp47 protein sensitivity specificity syphilis PCR
author_facet	Angèle Gayet-Ageron Patrice Sednaoui Stephan Lautenschlager Tristan Ferry Laurence Toutous-Trellu Matthias Cavassini Fatima Yassir Begoña Martinez de Tejada Stéphane Emonet Christophe Combescure Jacques Schrenzel Thomas Perneger
author_sort	Angèle Gayet-Ageron
title	Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title_short	Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title_full	Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title_fullStr	Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title_full_unstemmed	Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title_sort	use of treponema pallidum pcr in testing of ulcers for diagnosis of primary syphilis
publisher	Centers for Disease Control and Prevention
series	Emerging Infectious Diseases
issn	1080-6040 1080-6059
publishDate	2015-01-01
description	Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM.
topic	Treponema pallidum Tp47 protein sensitivity specificity syphilis PCR
url	https://wwwnc.cdc.gov/eid/article/21/1/14-0790_article
work_keys_str_mv	AT angelegayetageron useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT patricesednaoui useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT stephanlautenschlager useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT tristanferry useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT laurencetoutoustrellu useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT matthiascavassini useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT fatimayassir useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT begonamartinezdetejada useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT stephaneemonet useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT christophecombescure useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT jacquesschrenzel useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis AT thomasperneger useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
_version_	1724902966248341504

Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis

Similar Items