Formation of the Immunosuppressive Microenvironment of Classic Hodgkin Lymphoma and Therapeutic Approaches to Counter It

Formation of the Immunosuppressive Microenvironment of Classic Hodgkin Lymphoma and Therapeutic Approaches to Counter It

Classic Hodgkin lymphoma (cHL) is characterized by a few tumor cells surrounded by a protective, immunosuppressive tumor microenvironment composed of normal cells that are an active part of the disease. Hodgkin and Reed–Sternberg (HRS) cells evade the immune system through a variety of dif...

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Bibliographic Details
Main Authors: Donatella Aldinucci, Cinzia Borghese, Naike Casagrande
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
Hodgkin lymphoma
tumor microenvironment
immune escape
tumor-associated macrophages
Online Access:https://www.mdpi.com/1422-0067/20/10/2416

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