Undenatured Type II Collagen Ameliorates Inflammatory Responses and Articular Cartilage Damage in the Rat Model of Osteoarthritis

Undenatured Type II Collagen Ameliorates Inflammatory Responses and Articular Cartilage Damage in the Rat Model of Osteoarthritis

Osteoarthritis (OA) is an age-related joint disease that includes gradual disruption of the articular cartilage and the resulting pain. The present study was designed to test the effects of undenatured type II collagen (UC-II®) on joint inflammation in the monoiodoacetate (MIA) OA model. We also inv...

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Bibliographic Details
Main Authors: Cemal Orhan, Vijaya Juturu, Emre Sahin, Mehmet Tuzcu, Ibrahim Hanifi Ozercan, Ali Said Durmus, Nurhan Sahin, Kazim Sahin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Veterinary Science
Subjects:
osteoarthritis
inflammation
MIA
Nf-κB
UC-II
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.617789/full

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