Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus

Macrophage activation syndrome (MAS) is known to be a severe and potentially life-threatening complication of rheumatic disorder, especially systemic juvenile rheumatoid arthritis. It is very rare for MAS to be an initial presentation of systemic lupus erythematosus (SLE). Here, we report a 14-year-...

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Main Authors: Say-Tin Yeap, Jiunn-Ming Sheen, Ho-Chang Kuo, Kao-Pin Hwang, Kuender D. Yang, Hong-Ren Yu
Format: Article
Language:English
Published: Elsevier 2008-04-01
Series:Pediatrics and Neonatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957208600108
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spelling doaj-8c627d6fd00940189a7b27706d13a77d2020-11-24T22:57:45ZengElsevierPediatrics and Neonatology1875-95722008-04-01492394210.1016/S1875-9572(08)60010-8Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus ErythematosusSay-Tin YeapJiunn-Ming SheenHo-Chang KuoKao-Pin HwangKuender D. YangHong-Ren YuMacrophage activation syndrome (MAS) is known to be a severe and potentially life-threatening complication of rheumatic disorder, especially systemic juvenile rheumatoid arthritis. It is very rare for MAS to be an initial presentation of systemic lupus erythematosus (SLE). Here, we report a 14-year-old girl in whom MAS developed as an initial presentation of SLE. With early diagnosis and administration of cyclosporine A, she had a fair outcome. Further testing showed positive anti-dsDNA about 8 months later.http://www.sciencedirect.com/science/article/pii/S1875957208600108cyclosporine Amacrophage activation syndromesystemic lupus erythematosustype V hyperlipo-proteinemia
collection DOAJ
language English
format Article
sources DOAJ
author Say-Tin Yeap
Jiunn-Ming Sheen
Ho-Chang Kuo
Kao-Pin Hwang
Kuender D. Yang
Hong-Ren Yu
spellingShingle Say-Tin Yeap
Jiunn-Ming Sheen
Ho-Chang Kuo
Kao-Pin Hwang
Kuender D. Yang
Hong-Ren Yu
Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus
Pediatrics and Neonatology
cyclosporine A
macrophage activation syndrome
systemic lupus erythematosus
type V hyperlipo-proteinemia
author_facet Say-Tin Yeap
Jiunn-Ming Sheen
Ho-Chang Kuo
Kao-Pin Hwang
Kuender D. Yang
Hong-Ren Yu
author_sort Say-Tin Yeap
title Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus
title_short Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus
title_full Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus
title_fullStr Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus
title_full_unstemmed Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus
title_sort macrophage activation syndrome as initial presentation of systemic lupus erythematosus
publisher Elsevier
series Pediatrics and Neonatology
issn 1875-9572
publishDate 2008-04-01
description Macrophage activation syndrome (MAS) is known to be a severe and potentially life-threatening complication of rheumatic disorder, especially systemic juvenile rheumatoid arthritis. It is very rare for MAS to be an initial presentation of systemic lupus erythematosus (SLE). Here, we report a 14-year-old girl in whom MAS developed as an initial presentation of SLE. With early diagnosis and administration of cyclosporine A, she had a fair outcome. Further testing showed positive anti-dsDNA about 8 months later.
topic cyclosporine A
macrophage activation syndrome
systemic lupus erythematosus
type V hyperlipo-proteinemia
url http://www.sciencedirect.com/science/article/pii/S1875957208600108
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