IgaA negatively regulates the Rcs Phosphorelay via contact with the RcsD Phosphotransfer Protein.

Two-component systems and phosphorelays play central roles in the ability of bacteria to rapidly respond to changing environments. In E. coli and related enterobacteria, the complex Rcs phosphorelay is a critical player in the bacterial response to antimicrobial peptides, beta-lactam antibiotics, an...

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Bibliographic Details
Main Authors: Erin A Wall, Nadim Majdalani, Susan Gottesman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008610