Improving gene expression data interpretation by finding latent factors that co-regulate gene modules with clinical factors

<p>Abstract</p> <p>Background</p> <p>In the analysis of high-throughput data with a clinical outcome, researchers mostly focus on genes/proteins that show first-order relations with the clinical outcome. While this approach yields biomarkers and biological mechanisms th...

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Bibliographic Details
Main Authors: Yu Tianwei, Bai Yun
Format: Article
Language:English
Published: BMC 2011-11-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/563