Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature

Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature

We present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopen...

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Main Authors: Michael Gilbertson, Annabel Tuckfield, Surender Juneja
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2012/167653
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spelling doaj-8c89db04c7b54611a063cb6d488056282020-11-24T20:56:50ZengHindawi LimitedCase Reports in Hematology2090-65602090-65792012-01-01201210.1155/2012/167653167653Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the LiteratureMichael Gilbertson0Annabel Tuckfield1Surender Juneja2Department of Diagnostic Haematology, The Royal Melbourne Hospital, Parkville, VIC 3050, AustraliaDepartment of Diagnostic Haematology, The Royal Melbourne Hospital, Parkville, VIC 3050, AustraliaDepartment of Diagnostic Haematology, The Royal Melbourne Hospital, Parkville, VIC 3050, AustraliaWe present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopenia with multilineage dysplasia, with a relatively uncommon associated cytogenetic lesion t(1;7). We present the case and review the literature of this cytogenetic lesion.http://dx.doi.org/10.1155/2012/167653
collection DOAJ
language English
format Article
sources DOAJ
author Michael Gilbertson
Annabel Tuckfield
Surender Juneja
spellingShingle Michael Gilbertson
Annabel Tuckfield
Surender Juneja
Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
Case Reports in Hematology
author_facet Michael Gilbertson
Annabel Tuckfield
Surender Juneja
author_sort Michael Gilbertson
title Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title_short Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title_full Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title_fullStr Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title_full_unstemmed Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
title_sort myelodysplastic syndrome with t(1;7) associated with marked dysmegakarypoiesis & severe thrombocytopenia: a case report and review of the literature
publisher Hindawi Limited
series Case Reports in Hematology
issn 2090-6560
2090-6579
publishDate 2012-01-01
description We present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopenia with multilineage dysplasia, with a relatively uncommon associated cytogenetic lesion t(1;7). We present the case and review the literature of this cytogenetic lesion.
url http://dx.doi.org/10.1155/2012/167653
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AT annabeltuckfield myelodysplasticsyndromewitht17associatedwithmarkeddysmegakarypoiesisseverethrombocytopeniaacasereportandreviewoftheliterature
AT surenderjuneja myelodysplasticsyndromewitht17associatedwithmarkeddysmegakarypoiesisseverethrombocytopeniaacasereportandreviewoftheliterature
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