Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature
We present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopen...
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2012-01-01
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Series: | Case Reports in Hematology |
Online Access: | http://dx.doi.org/10.1155/2012/167653 |
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doaj-8c89db04c7b54611a063cb6d488056282020-11-24T20:56:50ZengHindawi LimitedCase Reports in Hematology2090-65602090-65792012-01-01201210.1155/2012/167653167653Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the LiteratureMichael Gilbertson0Annabel Tuckfield1Surender Juneja2Department of Diagnostic Haematology, The Royal Melbourne Hospital, Parkville, VIC 3050, AustraliaDepartment of Diagnostic Haematology, The Royal Melbourne Hospital, Parkville, VIC 3050, AustraliaDepartment of Diagnostic Haematology, The Royal Melbourne Hospital, Parkville, VIC 3050, AustraliaWe present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopenia with multilineage dysplasia, with a relatively uncommon associated cytogenetic lesion t(1;7). We present the case and review the literature of this cytogenetic lesion.http://dx.doi.org/10.1155/2012/167653 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Michael Gilbertson Annabel Tuckfield Surender Juneja |
spellingShingle |
Michael Gilbertson Annabel Tuckfield Surender Juneja Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature Case Reports in Hematology |
author_facet |
Michael Gilbertson Annabel Tuckfield Surender Juneja |
author_sort |
Michael Gilbertson |
title |
Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature |
title_short |
Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature |
title_full |
Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature |
title_fullStr |
Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature |
title_full_unstemmed |
Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature |
title_sort |
myelodysplastic syndrome with t(1;7) associated with marked dysmegakarypoiesis & severe thrombocytopenia: a case report and review of the literature |
publisher |
Hindawi Limited |
series |
Case Reports in Hematology |
issn |
2090-6560 2090-6579 |
publishDate |
2012-01-01 |
description |
We present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopenia with multilineage dysplasia, with a relatively uncommon associated cytogenetic lesion t(1;7). We present the case and review the literature of this cytogenetic lesion. |
url |
http://dx.doi.org/10.1155/2012/167653 |
work_keys_str_mv |
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1716789521583964160 |