Bicuspid aortic valve disease
The prevalence of bicuspid aortic valve (BAV) disease is 0.5 - 2% of the population with a 3:1 male predominance. The genetic basis remains unknown although 9% of families have more than one affected individual. Life expectancy in patients with BAV is similar to the general population with a 10-year...
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South African Heart Association
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doaj-8cab967fef414495b22499d96f43db742020-11-25T00:28:00ZengSouth African Heart AssociationSA Heart Journal1996-67412071-46022017-08-01142768510.24170/14-2-2496Bicuspid aortic valve diseaseLee, James C. 0Otto, Catherine M. 1University of WashingtonUniversity of WashingtonThe prevalence of bicuspid aortic valve (BAV) disease is 0.5 - 2% of the population with a 3:1 male predominance. The genetic basis remains unknown although 9% of families have more than one affected individual. Life expectancy in patients with BAV is similar to the general population with a 10-year survival of over 95%. Adverse outcomes are most often due to aortic stenosis late in life, aortic regurgitation in young adulthood or endocarditis in a small number of patients. The BAV syndrome is also associated with an aortopathy characterised by aortic dilation and an increased risk of aortic dissection. Clinical management of patients with a BAV focuses on periodic evaluation of valve function and aortic size, patient education about the expected disease course, prevention of endocarditis and optimal timing of aortic valve replacement for stenosis and/or regurgitation; with concurrent root replacement if aortic dilation (>4.5cm diameter) is present. In addition, aortic root replacement is recommended if aortic diameter exceeds 5.5cm, even if aortic valve function remains normal. https://www.journals.ac.za/index.php/SAHJ/article/view/2496Bicuspid aortic valve diseaseBicuspid aortic valve patientsaortic valve disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Lee, James C. Otto, Catherine M. |
spellingShingle |
Lee, James C. Otto, Catherine M. Bicuspid aortic valve disease SA Heart Journal Bicuspid aortic valve disease Bicuspid aortic valve patients aortic valve disease |
author_facet |
Lee, James C. Otto, Catherine M. |
author_sort |
Lee, James C. |
title |
Bicuspid aortic valve disease |
title_short |
Bicuspid aortic valve disease |
title_full |
Bicuspid aortic valve disease |
title_fullStr |
Bicuspid aortic valve disease |
title_full_unstemmed |
Bicuspid aortic valve disease |
title_sort |
bicuspid aortic valve disease |
publisher |
South African Heart Association |
series |
SA Heart Journal |
issn |
1996-6741 2071-4602 |
publishDate |
2017-08-01 |
description |
The prevalence of bicuspid aortic valve (BAV) disease is 0.5 - 2% of the population with a 3:1 male predominance. The genetic basis remains unknown although 9% of families have more than one affected individual. Life expectancy in patients with BAV is similar to the general population with a 10-year survival of over 95%. Adverse outcomes are most often due to aortic stenosis late in life, aortic regurgitation in young adulthood or endocarditis in a small number of patients. The BAV syndrome is also associated with an aortopathy characterised by aortic dilation and an increased risk of aortic dissection. Clinical management of patients with a BAV focuses on periodic evaluation of valve function and aortic size, patient education about the expected disease course, prevention of endocarditis and optimal timing of aortic valve replacement for stenosis and/or regurgitation; with concurrent root replacement if aortic dilation (>4.5cm diameter) is present. In addition, aortic root replacement is recommended if aortic diameter exceeds 5.5cm, even if aortic valve function remains normal.
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topic |
Bicuspid aortic valve disease Bicuspid aortic valve patients aortic valve disease |
url |
https://www.journals.ac.za/index.php/SAHJ/article/view/2496 |
work_keys_str_mv |
AT leejamesc bicuspidaorticvalvedisease AT ottocatherinem bicuspidaorticvalvedisease |
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1725337318340952064 |