Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features

Background. Hyperparathyroidism is underdiagnosed in pregnancy, yet early diagnosis is necessary for the potentially severe sequelae of hypercalcemia for both the woman and fetus. Case. A 31-year-old, gravida 3, para 0-0-2-0 at 32 weeks and 3 days of gestation, presented with preeclampsia with sever...

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Main Authors: Andrew G. Dale, Bradley D. Holbrook, Lauren Sobel, Valerie J. Rappaport
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2017/6061313
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spelling doaj-8cc9c15f591b41deb1b02af0b0d15bc02020-11-24T22:54:14ZengHindawi LimitedCase Reports in Obstetrics and Gynecology2090-66842090-66922017-01-01201710.1155/2017/60613136061313Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe FeaturesAndrew G. Dale0Bradley D. Holbrook1Lauren Sobel2Valerie J. Rappaport3Department of Obstetrics & Gynecology, University of New Mexico, Albuquerque, NM, USADepartment of Obstetrics & Gynecology, University of New Mexico, Albuquerque, NM, USATouro University College of Osteopathic Medicine, Vallejo, CA, USADepartment of Obstetrics & Gynecology, University of New Mexico, Albuquerque, NM, USABackground. Hyperparathyroidism is underdiagnosed in pregnancy, yet early diagnosis is necessary for the potentially severe sequelae of hypercalcemia for both the woman and fetus. Case. A 31-year-old, gravida 3, para 0-0-2-0 at 32 weeks and 3 days of gestation, presented with preeclampsia with severe features concomitant with acute pancreatitis and known diabetes mellitus type 2. She was stabilized and delivered. In the postpartum period, her total calcium level remained elevated. Ionized calcium levels and parathyroid hormone levels were also elevated, and she was diagnosed with hyperparathyroidism. Conclusion. Hyperparathyroidism and hypercalcemia are risk factors for pancreatitis. Women who develop pancreatitis during pregnancy are at increased risk of developing preeclampsia. If elevated serum calcium is noted, it should be confirmed with ionized calcium level and parathyroid hormones as ionized calcium levels are unaffected by pregnancy.http://dx.doi.org/10.1155/2017/6061313
collection DOAJ
language English
format Article
sources DOAJ
author Andrew G. Dale
Bradley D. Holbrook
Lauren Sobel
Valerie J. Rappaport
spellingShingle Andrew G. Dale
Bradley D. Holbrook
Lauren Sobel
Valerie J. Rappaport
Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
Case Reports in Obstetrics and Gynecology
author_facet Andrew G. Dale
Bradley D. Holbrook
Lauren Sobel
Valerie J. Rappaport
author_sort Andrew G. Dale
title Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title_short Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title_full Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title_fullStr Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title_full_unstemmed Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title_sort hyperparathyroidism in pregnancy leading to pancreatitis and preeclampsia with severe features
publisher Hindawi Limited
series Case Reports in Obstetrics and Gynecology
issn 2090-6684
2090-6692
publishDate 2017-01-01
description Background. Hyperparathyroidism is underdiagnosed in pregnancy, yet early diagnosis is necessary for the potentially severe sequelae of hypercalcemia for both the woman and fetus. Case. A 31-year-old, gravida 3, para 0-0-2-0 at 32 weeks and 3 days of gestation, presented with preeclampsia with severe features concomitant with acute pancreatitis and known diabetes mellitus type 2. She was stabilized and delivered. In the postpartum period, her total calcium level remained elevated. Ionized calcium levels and parathyroid hormone levels were also elevated, and she was diagnosed with hyperparathyroidism. Conclusion. Hyperparathyroidism and hypercalcemia are risk factors for pancreatitis. Women who develop pancreatitis during pregnancy are at increased risk of developing preeclampsia. If elevated serum calcium is noted, it should be confirmed with ionized calcium level and parathyroid hormones as ionized calcium levels are unaffected by pregnancy.
url http://dx.doi.org/10.1155/2017/6061313
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