Green and Facile Synthesis of Dendritic and Branched Gold Nanoparticles by Gelatin and Investigation of Their Biocompatibility on Fibroblast Cells
In this work, gold nanostar (AuNPs) and gold nanodendrites were synthesized by one-pot and environmentally friendly approach in the presence of gelatin. Influence of gelatin concentrations and reaction conditions on the growth of branched (AuNPs) were investigated further. Interestingly, the convers...
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doaj-8cd2ad10e52c42e3af2f7c8547d9a7962020-11-24T20:53:57ZengMDPI AGProcesses2227-97172019-09-017963110.3390/pr7090631pr7090631Green and Facile Synthesis of Dendritic and Branched Gold Nanoparticles by Gelatin and Investigation of Their Biocompatibility on Fibroblast CellsQuoc Khuong Vo0My Nuong Nguyen Thi1Phuong Phong Nguyen Thi2Duy Trinh Nguyen3Faculty of Chemistry, Ho Chi Minh City University of Science, Vietnam National University-Ho Chi Minh City, Ho Chi Minh City 700000, VietnamFaculty of Biology and Biotechnology, Ho Chi Minh City University of Science, Vietnam National University-Ho Chi Minh City, Ho Chi Minh City 700000, VietnamFaculty of Chemistry, Ho Chi Minh City University of Science, Vietnam National University-Ho Chi Minh City, Ho Chi Minh City 700000, VietnamNTT Hi-Tech Institute, Nguyen Tat Thanh University, Ho Chi Minh City 700000, VietnamIn this work, gold nanostar (AuNPs) and gold nanodendrites were synthesized by one-pot and environmentally friendly approach in the presence of gelatin. Influence of gelatin concentrations and reaction conditions on the growth of branched (AuNPs) were investigated further. Interestingly, the conversion of morphology between dendritic and branched nanostructure can be attained by changing the pH value of gelatin solution. The role of gelatin as a protecting agent through the electrostatic and steric interaction was also revealed. Branched nanoparticles were characterized by surface plasmon resonance spectroscopy (SPR), transmission electron microscopy (TEM), XRD, dynamic light scattering (DLS) and zeta-potential. The chemical interaction of gelatin with branched gold nanoparticles was analyzed by Fourier transform infrared spectroscopy (FT-IT) technique. Ultraviolet visible spectroscopy results indicated the formation of branched gold nanoparticles with the maximum surface plasmon resonance peak at 575−702 nm. The structure of both nanodendrites and nanostars were determined by TEM. The crystal sizes of nano-star ranged from 42 to 55 nm and the nanodendrites sizes were about 75−112 nm. Based on the characterizations, a growth mechanism could be proposed to explain morphology evolutions of branched AuNPs. Moreover, the branched AuNPs is high viability at 100 μg/mL concentration when performed by the SRB assay with human foreskin fibroblast cells.https://www.mdpi.com/2227-9717/7/9/631nanodendritesnanostarfibroblast cellsgelatinone-pot synthesis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Quoc Khuong Vo My Nuong Nguyen Thi Phuong Phong Nguyen Thi Duy Trinh Nguyen |
spellingShingle |
Quoc Khuong Vo My Nuong Nguyen Thi Phuong Phong Nguyen Thi Duy Trinh Nguyen Green and Facile Synthesis of Dendritic and Branched Gold Nanoparticles by Gelatin and Investigation of Their Biocompatibility on Fibroblast Cells Processes nanodendrites nanostar fibroblast cells gelatin one-pot synthesis |
author_facet |
Quoc Khuong Vo My Nuong Nguyen Thi Phuong Phong Nguyen Thi Duy Trinh Nguyen |
author_sort |
Quoc Khuong Vo |
title |
Green and Facile Synthesis of Dendritic and Branched Gold Nanoparticles by Gelatin and Investigation of Their Biocompatibility on Fibroblast Cells |
title_short |
Green and Facile Synthesis of Dendritic and Branched Gold Nanoparticles by Gelatin and Investigation of Their Biocompatibility on Fibroblast Cells |
title_full |
Green and Facile Synthesis of Dendritic and Branched Gold Nanoparticles by Gelatin and Investigation of Their Biocompatibility on Fibroblast Cells |
title_fullStr |
Green and Facile Synthesis of Dendritic and Branched Gold Nanoparticles by Gelatin and Investigation of Their Biocompatibility on Fibroblast Cells |
title_full_unstemmed |
Green and Facile Synthesis of Dendritic and Branched Gold Nanoparticles by Gelatin and Investigation of Their Biocompatibility on Fibroblast Cells |
title_sort |
green and facile synthesis of dendritic and branched gold nanoparticles by gelatin and investigation of their biocompatibility on fibroblast cells |
publisher |
MDPI AG |
series |
Processes |
issn |
2227-9717 |
publishDate |
2019-09-01 |
description |
In this work, gold nanostar (AuNPs) and gold nanodendrites were synthesized by one-pot and environmentally friendly approach in the presence of gelatin. Influence of gelatin concentrations and reaction conditions on the growth of branched (AuNPs) were investigated further. Interestingly, the conversion of morphology between dendritic and branched nanostructure can be attained by changing the pH value of gelatin solution. The role of gelatin as a protecting agent through the electrostatic and steric interaction was also revealed. Branched nanoparticles were characterized by surface plasmon resonance spectroscopy (SPR), transmission electron microscopy (TEM), XRD, dynamic light scattering (DLS) and zeta-potential. The chemical interaction of gelatin with branched gold nanoparticles was analyzed by Fourier transform infrared spectroscopy (FT-IT) technique. Ultraviolet visible spectroscopy results indicated the formation of branched gold nanoparticles with the maximum surface plasmon resonance peak at 575−702 nm. The structure of both nanodendrites and nanostars were determined by TEM. The crystal sizes of nano-star ranged from 42 to 55 nm and the nanodendrites sizes were about 75−112 nm. Based on the characterizations, a growth mechanism could be proposed to explain morphology evolutions of branched AuNPs. Moreover, the branched AuNPs is high viability at 100 μg/mL concentration when performed by the SRB assay with human foreskin fibroblast cells. |
topic |
nanodendrites nanostar fibroblast cells gelatin one-pot synthesis |
url |
https://www.mdpi.com/2227-9717/7/9/631 |
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