Modulating the Biologic Activity of Mesenteric Lymph after Traumatic Shock Decreases Systemic Inflammation and End Organ Injury.
Trauma/hemorrhagic shock (T/HS) causes the release of pro-inflammatory mediators into the mesenteric lymph (ML), triggering a systemic inflammatory response and acute lung injury (ALI). Direct and pharmacologic vagal nerve stimulation prevents gut barrier failure and alters the biologic activity of...
Main Authors: | Simone Langness, Todd W Costantini, Koji Morishita, Brian P Eliceiri, Raul Coimbra |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5158049?pdf=render |
Similar Items
-
Mesenteric lymph reperfusion exacerbates spleen injury caused by superior mesenteric artery occlusion shock
by: L.L. Li, et al.
Published: (2014-05-01) -
Hydrogen sulfide in posthemorrhagic shock mesenteric lymph drainage alleviates kidney injury in rats
by: B. Han, et al.
Published: (2015-07-01) -
Mesenteric Lymph Drainage Alleviates Acute Kidney Injury Induced by Hemorrhagic Shock without Resuscitation
by: Zi-Gang Zhao, et al.
Published: (2014-01-01) -
Transcriptome Analysis Revealed Inflammation Is Involved in the Impairment of Human Umbilical Vein Endothelial Cells Induced by Post-hemorrhagic Shock Mesenteric Lymph
by: Qi Wang, et al.
Published: (2020-09-01) -
Gut Ischemia Reperfusion Injury Induces Lung Inflammation via Mesenteric Lymph-Mediated Neutrophil Activation
by: Yonggang Ma, et al.
Published: (2020-09-01)