Molecular Weight-Dependent Immunostimulative Activity of Low Molecular Weight Chitosan via Regulating NF-κB and AP-1 Signaling Pathways in RAW264.7 Macrophages

Molecular Weight-Dependent Immunostimulative Activity of Low Molecular Weight Chitosan via Regulating NF-κB and AP-1 Signaling Pathways in RAW264.7 Macrophages

Chitosan and its derivatives such as low molecular weight chitosans (LMWCs) have been found to possess many important biological properties, such as antioxidant and antitumor effects. In our previous study, LMWCs were found to elicit a strong immunomodulatory response in macrophages dependent on mol...

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Bibliographic Details
Main Authors: Bin Zheng, Zheng-Shun Wen, Yun-Juan Huang, Mei-Sheng Xia, Xing-Wei Xiang, You-Le Qu
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Marine Drugs
Subjects:
immunostimulative activity
NF-κB/AP-1
molecular weight
low molecular weight chitosans
macrophages
Online Access:http://www.mdpi.com/1660-3397/14/9/169

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