Radiolabeled Gold Nanoparticles for Imaging and Therapy of Cancer
In the Last decades, nanotechnology has provided novel and alternative methodologies and tools in the field of medical oncology, in order to tackle the issues regarding the control and treatment of cancer in modern society. In particular, the use of gold nanoparticles (AuNPs) in radiopharmaceutical...
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doaj-8cec2caa7e3c4dd3a3e0fd220d35bbce2020-12-23T00:03:28ZengMDPI AGMaterials1996-19442021-12-01144410.3390/ma14010004Radiolabeled Gold Nanoparticles for Imaging and Therapy of CancerFrancisco Silva0Maria Paula Cabral Campello1António Paulo2CTN—Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10 (km 139,7), 2695-066 Bobadela, PortugalCTN—Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10 (km 139,7), 2695-066 Bobadela, PortugalCTN—Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10 (km 139,7), 2695-066 Bobadela, PortugalIn the Last decades, nanotechnology has provided novel and alternative methodologies and tools in the field of medical oncology, in order to tackle the issues regarding the control and treatment of cancer in modern society. In particular, the use of gold nanoparticles (AuNPs) in radiopharmaceutical development has provided various nanometric platforms for the delivery of medically relevant radioisotopes for SPECT/PET diagnosis and/or radionuclide therapy. In this review, we intend to provide insight on the methodologies used to obtain and characterize radiolabeled AuNPs while reporting relevant examples of AuNPs developed during the last decade for applications in nuclear imaging and/or radionuclide therapy, and highlighting the most significant preclinical studies and results.https://www.mdpi.com/1996-1944/14/1/4gold nanoparticles (AuNPs)nuclear imagingradionuclide therapynanomedicinenanotechnology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Francisco Silva Maria Paula Cabral Campello António Paulo |
spellingShingle |
Francisco Silva Maria Paula Cabral Campello António Paulo Radiolabeled Gold Nanoparticles for Imaging and Therapy of Cancer Materials gold nanoparticles (AuNPs) nuclear imaging radionuclide therapy nanomedicine nanotechnology |
author_facet |
Francisco Silva Maria Paula Cabral Campello António Paulo |
author_sort |
Francisco Silva |
title |
Radiolabeled Gold Nanoparticles for Imaging and Therapy of Cancer |
title_short |
Radiolabeled Gold Nanoparticles for Imaging and Therapy of Cancer |
title_full |
Radiolabeled Gold Nanoparticles for Imaging and Therapy of Cancer |
title_fullStr |
Radiolabeled Gold Nanoparticles for Imaging and Therapy of Cancer |
title_full_unstemmed |
Radiolabeled Gold Nanoparticles for Imaging and Therapy of Cancer |
title_sort |
radiolabeled gold nanoparticles for imaging and therapy of cancer |
publisher |
MDPI AG |
series |
Materials |
issn |
1996-1944 |
publishDate |
2021-12-01 |
description |
In the Last decades, nanotechnology has provided novel and alternative methodologies and tools in the field of medical oncology, in order to tackle the issues regarding the control and treatment of cancer in modern society. In particular, the use of gold nanoparticles (AuNPs) in radiopharmaceutical development has provided various nanometric platforms for the delivery of medically relevant radioisotopes for SPECT/PET diagnosis and/or radionuclide therapy. In this review, we intend to provide insight on the methodologies used to obtain and characterize radiolabeled AuNPs while reporting relevant examples of AuNPs developed during the last decade for applications in nuclear imaging and/or radionuclide therapy, and highlighting the most significant preclinical studies and results. |
topic |
gold nanoparticles (AuNPs) nuclear imaging radionuclide therapy nanomedicine nanotechnology |
url |
https://www.mdpi.com/1996-1944/14/1/4 |
work_keys_str_mv |
AT franciscosilva radiolabeledgoldnanoparticlesforimagingandtherapyofcancer AT mariapaulacabralcampello radiolabeledgoldnanoparticlesforimagingandtherapyofcancer AT antoniopaulo radiolabeledgoldnanoparticlesforimagingandtherapyofcancer |
_version_ |
1724373903482028032 |