Amylase-Sensitive Polymeric Nanoparticles Based on Dextran Sulfate and Doxorubicin with Anticoagulant Activity

Amylase-Sensitive Polymeric Nanoparticles Based on Dextran Sulfate and Doxorubicin with Anticoagulant Activity

This study looked into the synthesis and study of Dextrane Sulfate−Doxorubicin Nanoparticles (DS−Dox NP) that are sensitive to amylase and show anticoagulant properties. The particles were obtained by the method of solvent replacement. They had a size of 305 ± 58 nm, wit...

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Bibliographic Details
Main Authors:	Nikolay A. Pyataev, Pavel S. Petrov, Olga V. Minaeva, Mikhail N. Zharkov, Oleg A. Kulikov, Axeksandr V. Kokorev, Ekaterina P. Brodovskaya, Ivan A. Yurlov, Ilya V. Syusin, Andrey V. Zaborovskiy, Larisa A. Balykova
Format:	Article
Language:	English
Published:	MDPI AG 2019-05-01
Series:	Polymers
Subjects:	doxorubicin dextran sulfate nanoparticles amylase cytotoxicity ascitic hepatoma heparin-like effect
Online Access:	https://www.mdpi.com/2073-4360/11/5/921

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