IP-10 and CXCR3 signaling inhibit Zika virus replication in human prostate cells.

IP-10 and CXCR3 signaling inhibit Zika virus replication in human prostate cells.

Our previous studies have shown that Zika virus (ZIKV) replicates in human prostate cells, suggesting that the prostate may serve as a long-term reservoir for virus transmission. Here, we demonstrated that the innate immune responses generated to three distinct ZIKV strains (all isolated from human...

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Bibliographic Details
Main Authors: Jennifer L Spencer Clinton, Linda L Tran, Megan B Vogt, David R Rowley, Jason T Kimata, Rebecca Rico-Hesse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244587

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