Seroepidemiological study of toxoplasmosis in hemodialysis patients of Ahvaz, Southwest of Iran

Introduction: Toxoplasma gondii infects most warm-blooded vertebrates. Because of the immunodeficiency in hemodialysis patients, these individuals are at higher risk for reactivating chronic toxoplasmosis. Thus, the aim of this study was to investigate seroepidemiology of toxoplasmosis in hemodialys...

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Main Authors: Forough Kazemi, Somayeh Fallahizadeh, Mohammad Hosein Feizhadad
Format: Article
Language:English
Published: Negah Institute for Scientific Communication 2018-01-01
Series:International Journal of Biomedicine and Public Health
Subjects:
Online Access:http://www.ijbmph.com/article_55340_114a930ebec5e675121a77f42a91cf47.pdf
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spelling doaj-8d201a85b1af458e9322ec9895a0f1b22020-11-25T04:08:44ZengNegah Institute for Scientific CommunicationInternational Journal of Biomedicine and Public Health2588-53752588-53752018-01-0111121610.22631/ijbmph.2018.5534055340Seroepidemiological study of toxoplasmosis in hemodialysis patients of Ahvaz, Southwest of IranForough Kazemi0Somayeh Fallahizadeh1Mohammad Hosein Feizhadad2Department of Parasitology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran.Department of Parasitology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran.Department of Parasitology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran.Introduction: Toxoplasma gondii infects most warm-blooded vertebrates. Because of the immunodeficiency in hemodialysis patients, these individuals are at higher risk for reactivating chronic toxoplasmosis. Thus, the aim of this study was to investigate seroepidemiology of toxoplasmosis in hemodialysis patients of Ahvaz, southwest of Iran during 2015-2016. Methods: This is a cross-sectional study. A total of 160 participants, 80 hemodialysis patients (test group) and 80 healthy persons (control group) were randomly selected. IgG and IgM against T. gondii was measured by CLIA (Chemiluminescence) and ELISA (Enzyme-linked immunosorbent assay) tests. To analyze the data from Chi-square test, and SPSS statistical software of version 21 was used. Results: In hemodialysis patients, 35 (43.8%) and 25 (31.3%) were positive for the antibody of IgG by ELISA and CLIA, respectively. In healthy individuals, a positive result of 22 (27.5%) and 13 (16.3%) were obtained by ELISA and CLIA, respectively. In hemodialysis patients, 5 (6.3%) and 4 (5%) was positive by ELISA and by CLIA, respectively. In healthy individuals, a positive of 4 (5%) were obtained by ELISA and CLIA. The antibodies of IgG in hemodialysis patients was significantly higher than healthy individuals by ELISA and CLIA (P <.05). Conclusion: The prevalence of Toxoplasma in hemodialysis patients was higher than healthy subjects. Our finding showed a relatively high prevalence of the parasite among hemodialysis patients and healthy individuals in Ahvaz. So, the health authorities of Ahvaz city must pay more attention to control of the infection, especially in hemodialysis patients.http://www.ijbmph.com/article_55340_114a930ebec5e675121a77f42a91cf47.pdfseroepidemiologytoxoplasma gondiihemodialysisahvaziran
collection DOAJ
language English
format Article
sources DOAJ
author Forough Kazemi
Somayeh Fallahizadeh
Mohammad Hosein Feizhadad
spellingShingle Forough Kazemi
Somayeh Fallahizadeh
Mohammad Hosein Feizhadad
Seroepidemiological study of toxoplasmosis in hemodialysis patients of Ahvaz, Southwest of Iran
International Journal of Biomedicine and Public Health
seroepidemiology
toxoplasma gondii
hemodialysis
ahvaz
iran
author_facet Forough Kazemi
Somayeh Fallahizadeh
Mohammad Hosein Feizhadad
author_sort Forough Kazemi
title Seroepidemiological study of toxoplasmosis in hemodialysis patients of Ahvaz, Southwest of Iran
title_short Seroepidemiological study of toxoplasmosis in hemodialysis patients of Ahvaz, Southwest of Iran
title_full Seroepidemiological study of toxoplasmosis in hemodialysis patients of Ahvaz, Southwest of Iran
title_fullStr Seroepidemiological study of toxoplasmosis in hemodialysis patients of Ahvaz, Southwest of Iran
title_full_unstemmed Seroepidemiological study of toxoplasmosis in hemodialysis patients of Ahvaz, Southwest of Iran
title_sort seroepidemiological study of toxoplasmosis in hemodialysis patients of ahvaz, southwest of iran
publisher Negah Institute for Scientific Communication
series International Journal of Biomedicine and Public Health
issn 2588-5375
2588-5375
publishDate 2018-01-01
description Introduction: Toxoplasma gondii infects most warm-blooded vertebrates. Because of the immunodeficiency in hemodialysis patients, these individuals are at higher risk for reactivating chronic toxoplasmosis. Thus, the aim of this study was to investigate seroepidemiology of toxoplasmosis in hemodialysis patients of Ahvaz, southwest of Iran during 2015-2016. Methods: This is a cross-sectional study. A total of 160 participants, 80 hemodialysis patients (test group) and 80 healthy persons (control group) were randomly selected. IgG and IgM against T. gondii was measured by CLIA (Chemiluminescence) and ELISA (Enzyme-linked immunosorbent assay) tests. To analyze the data from Chi-square test, and SPSS statistical software of version 21 was used. Results: In hemodialysis patients, 35 (43.8%) and 25 (31.3%) were positive for the antibody of IgG by ELISA and CLIA, respectively. In healthy individuals, a positive result of 22 (27.5%) and 13 (16.3%) were obtained by ELISA and CLIA, respectively. In hemodialysis patients, 5 (6.3%) and 4 (5%) was positive by ELISA and by CLIA, respectively. In healthy individuals, a positive of 4 (5%) were obtained by ELISA and CLIA. The antibodies of IgG in hemodialysis patients was significantly higher than healthy individuals by ELISA and CLIA (P <.05). Conclusion: The prevalence of Toxoplasma in hemodialysis patients was higher than healthy subjects. Our finding showed a relatively high prevalence of the parasite among hemodialysis patients and healthy individuals in Ahvaz. So, the health authorities of Ahvaz city must pay more attention to control of the infection, especially in hemodialysis patients.
topic seroepidemiology
toxoplasma gondii
hemodialysis
ahvaz
iran
url http://www.ijbmph.com/article_55340_114a930ebec5e675121a77f42a91cf47.pdf
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