Anticonvulsant Action of GluN2A-Preferring Antagonist PEAQX in Developing Rats

Anticonvulsant Action of GluN2A-Preferring Antagonist PEAQX in Developing Rats

The GluN2A subunit of N-methyl-D-aspartate (NMDA) receptors becomes dominant during postnatal development, overgrowing the originally dominant GluN2B subunit. The aim of our study was to show changes of anticonvulsant action of the GluN2A subunit-preferring antagonist during postnatal development of...

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Bibliographic Details
Main Authors:	Pavel Mares, Grygoriy Tsenov, Hana Kubova
Format:	Article
Language:	English
Published:	MDPI AG 2021-03-01
Series:	Pharmaceutics
Subjects:	NMDA receptors GluN2A subunit anticonvulsant action pentylenetetrazol-induced seizures cortical epileptic afterdischarges immature rats
Online Access:	https://www.mdpi.com/1999-4923/13/3/415

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