Clinical Significance of Potential Unidentified HLA-G Isoforms Without α1 Domain but Containing Intron 4 in Colorectal Cancer Patients

Clinical Significance of Potential Unidentified HLA-G Isoforms Without α1 Domain but Containing Intron 4 in Colorectal Cancer Patients

The ectopic HLA-G expression in malignancies has been extensively explored and clinical significance of the molecule was widely acknowledged. Besides previously well-documented seven isoforms (HLA-G1~-G7), other novel isoforms of HLA-G have been reported but their clinical relavenace remians evaluat...

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Bibliographic Details
Main Authors: Aifen Lin, Xia Zhang, Rui-Li Zhang, Jian-Gang Zhang, Wen-Jun Zhou, Wei-Hua Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Oncology
Subjects:
HLA-G
isoform
antibodies
colorectal cancer
prognosis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00361/full

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