Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line.

Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line.

<h4>Background</h4>Exosomes play a major role in cell-to-cell communication, targeting cells to transfer exosomal molecules including proteins, mRNAs, and microRNAs (miRNAs) by an endocytosis-like pathway. miRNAs are small noncoding RNA molecules on average 22 nucleotides in length that...

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Main Authors: Keiichi Ohshima, Kanako Inoue, Akemi Fujiwara, Keiichi Hatakeyama, Kaori Kanto, Yuko Watanabe, Koji Muramatsu, Yorikane Fukuda, Shun-ichiro Ogura, Ken Yamaguchi, Tohru Mochizuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20949044/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20949044/pdf/?tool=EBI

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