Nutritional Therapy to Modulate Tryptophan Metabolism and Aryl Hydrocarbon-Receptor Signaling Activation in Human Diseases

Nutritional Therapy to Modulate Tryptophan Metabolism and Aryl Hydrocarbon-Receptor Signaling Activation in Human Diseases

The aryl hydrocarbon receptor (AhR) is a nuclear protein which, upon association with certain endogenous and exogenous ligands, translocates into the nucleus, binds DNA and regulates gene expression. Tryptophan (Trp) metabolites are one of the most important endogenous AhR ligands. The intestinal mi...

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Bibliographic Details
Main Authors: Mohammed Ghiboub, Charlotte M. Verburgt, Bruno Sovran, Marc A. Benninga, Wouter J. de Jonge, Johan E. Van Limbergen
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Nutrients
Subjects:
microbiota
tryptophan
AhR
nutritional therapy
human diseases
Online Access:https://www.mdpi.com/2072-6643/12/9/2846

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