Direct Evidence of Symmetry between Bilateral Human Corneas in Biomechanical Properties: A Comparison Study with Fresh Corneal Tissue
Purpose. To investigate the difference between the eyes from the same human with respect to the biomechanical properties of fresh corneal tissues and investigate the assumption of similarity of the corneal biomechanical properties between the eyes. Methods. Strip specimens extracted through a small...
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Online Access: | http://dx.doi.org/10.1155/2021/8891412 |
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doaj-8d6f5a367b4a4f5abe8169c1fd91eb482021-02-15T12:53:06ZengHindawi LimitedJournal of Ophthalmology2090-004X2090-00582021-01-01202110.1155/2021/88914128891412Direct Evidence of Symmetry between Bilateral Human Corneas in Biomechanical Properties: A Comparison Study with Fresh Corneal TissueChao Xue0Yaoqi Xiang1Yi Song2Min Shen3Di Wu4Yan Wang5Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaSchool of Mechanical Engineering, Tianjin University, Tianjin, ChinaClinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaSchool of Mechanical Engineering, Tianjin University, Tianjin, ChinaClinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaClinical College of Ophthalmology, Tianjin Medical University, Tianjin, ChinaPurpose. To investigate the difference between the eyes from the same human with respect to the biomechanical properties of fresh corneal tissues and investigate the assumption of similarity of the corneal biomechanical properties between the eyes. Methods. Strip specimens extracted through a small incision lenticule extraction (SMILE) surgery were tested using a uniaxial tensile test. The specimens were extracted vertically. Low-strain tangent modulus (LSTM), high-strain tangent modulus (HSTM), and tensile strength (σb) were the biomechanical parameters used in the comparison of the eyes from the same human. Results. Ninety corneal specimens from 45 persons were included in this study. The LSTM of the left and right eyes were 1.34 ± 0.52 and 1.37 ± 0.46 MPa, while the HSTM were 50.53 ± 7.51 and 49.41 ± 7.01 MPa, respectively. There was no significant difference between the eyes in terms of LSTM, HSTM, andσbP=0.813, 0.335, and 0.605, resp.. The LSTM and HSTM were significantly correlated with the spherical equivalent (SE) (P≤0.01, P=0.001, resp.). Conclusions. The assumption that the corneal biomechanical properties of the eyes from the same human are similar has been confirmed for the first time using fresh human corneal tissue. This finding may be useful in further biomechanical studies.http://dx.doi.org/10.1155/2021/8891412 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chao Xue Yaoqi Xiang Yi Song Min Shen Di Wu Yan Wang |
spellingShingle |
Chao Xue Yaoqi Xiang Yi Song Min Shen Di Wu Yan Wang Direct Evidence of Symmetry between Bilateral Human Corneas in Biomechanical Properties: A Comparison Study with Fresh Corneal Tissue Journal of Ophthalmology |
author_facet |
Chao Xue Yaoqi Xiang Yi Song Min Shen Di Wu Yan Wang |
author_sort |
Chao Xue |
title |
Direct Evidence of Symmetry between Bilateral Human Corneas in Biomechanical Properties: A Comparison Study with Fresh Corneal Tissue |
title_short |
Direct Evidence of Symmetry between Bilateral Human Corneas in Biomechanical Properties: A Comparison Study with Fresh Corneal Tissue |
title_full |
Direct Evidence of Symmetry between Bilateral Human Corneas in Biomechanical Properties: A Comparison Study with Fresh Corneal Tissue |
title_fullStr |
Direct Evidence of Symmetry between Bilateral Human Corneas in Biomechanical Properties: A Comparison Study with Fresh Corneal Tissue |
title_full_unstemmed |
Direct Evidence of Symmetry between Bilateral Human Corneas in Biomechanical Properties: A Comparison Study with Fresh Corneal Tissue |
title_sort |
direct evidence of symmetry between bilateral human corneas in biomechanical properties: a comparison study with fresh corneal tissue |
publisher |
Hindawi Limited |
series |
Journal of Ophthalmology |
issn |
2090-004X 2090-0058 |
publishDate |
2021-01-01 |
description |
Purpose. To investigate the difference between the eyes from the same human with respect to the biomechanical properties of fresh corneal tissues and investigate the assumption of similarity of the corneal biomechanical properties between the eyes. Methods. Strip specimens extracted through a small incision lenticule extraction (SMILE) surgery were tested using a uniaxial tensile test. The specimens were extracted vertically. Low-strain tangent modulus (LSTM), high-strain tangent modulus (HSTM), and tensile strength (σb) were the biomechanical parameters used in the comparison of the eyes from the same human. Results. Ninety corneal specimens from 45 persons were included in this study. The LSTM of the left and right eyes were 1.34 ± 0.52 and 1.37 ± 0.46 MPa, while the HSTM were 50.53 ± 7.51 and 49.41 ± 7.01 MPa, respectively. There was no significant difference between the eyes in terms of LSTM, HSTM, andσbP=0.813, 0.335, and 0.605, resp.. The LSTM and HSTM were significantly correlated with the spherical equivalent (SE) (P≤0.01, P=0.001, resp.). Conclusions. The assumption that the corneal biomechanical properties of the eyes from the same human are similar has been confirmed for the first time using fresh human corneal tissue. This finding may be useful in further biomechanical studies. |
url |
http://dx.doi.org/10.1155/2021/8891412 |
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