Detection of methylated septin 9 in tissue and plasma of colorectal patients with neoplasia and the relationship to the amount of circulating cell-free DNA.

Detection of methylated septin 9 in tissue and plasma of colorectal patients with neoplasia and the relationship to the amount of circulating cell-free DNA.

BACKGROUND:Determination of methylated Septin 9 (mSEPT9) in plasma has been shown to be a sensitive and specific biomarker for colorectal cancer (CRC). However, the relationship between methylated DNA in plasma and colon tissue of the same subjects has not been reported. METHODS:Plasma and matching...

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Main Authors: Kinga Tóth, Reinhold Wasserkort, Ferenc Sipos, Alexandra Kalmár, Barnabás Wichmann, Katalin Leiszter, Gábor Valcz, Márk Juhász, Pál Miheller, Árpád V Patai, Zsolt Tulassay, Béla Molnár
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4272286?pdf=render

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