Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation
Abstract Api5, is a known anti-apoptotic and nuclear protein that is responsible for inhibiting cell death in serum-starved conditions. The only known post-translational modification of Api5 is acetylation at lysine 251 (K251). K251 acetylation of Api5 is responsible for maintaining its stability wh...
Main Authors: | Virender Kumar Sharma, Mayurika Lahiri |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-95941-4 |
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