cGMP-dependent protein kinase type I is implicated in the regulation of the timing and quality of sleep and wakefulness.

cGMP-dependent protein kinase type I is implicated in the regulation of the timing and quality of sleep and wakefulness.

Many effects of nitric oxide (NO) are mediated by the activation of guanylyl cyclases and subsequent production of the second messenger cyclic guanosine-3',5'-monophosphate (cGMP). cGMP activates cGMP-dependent protein kinases (PRKGs), which can therefore be considered downstream effectors...

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Bibliographic Details
Main Authors: Sonja Langmesser, Paul Franken, Susanne Feil, Yann Emmenegger, Urs Albrecht, Robert Feil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2617781?pdf=render

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